in traditional chinese medicine, arsenous compounds, including arsenic trioxide (ato), are often used to treat many diseases, which are safe and effective. recently, studies have indicated that th17– il-17 involved in the pathogenesis and development of asthma. the goal of this study was to investigate the effect and mechanism of ato on asthma, especially the th17– il-17 axis. we used oval bumi...

abstract   background: cosmetic rhinoplasty is now carried out increasingly in an attempt to solve the psychological and social problems of people who are discontent with their nose. little is known about either the psychological status of persons who seek rhinoplasty or potential psychological changes following surgery. the challenge that faces surgeons, is how to identify, before surgical int...

i n m a n u f a c t u r i n g a c t i v i t i e s, i s s u e s s u c h a s t h e i n t e n s i t y o f c o m p e t i t i o n, r i s i n g a n d c h a n g i n g c u s t o m e r e x p e c t a t i o n s, a n d e v e r-i n c r e a s i n g t e c h n o l o g i c a l d e v e l o p m e n t s, i n t e n s i f y m a n u f a c t u r e r c o m m i t m e n t t o e l i m i n a t e d e f e c t s i n i t s p r...

objective(s):one of the major challenges in the field of vaccine design is choosing immunogenic antigens which can induce a proper immune response against complex targets like malignant cells or recondite diseases caused by protozoan parasites such as leishmaniasis. the aim of this study was to find a way to construct artificial liposome-based cells containing fragments of target’s cell membran...

inrtoduction developing countries and newly industrialized countries face the twin challenges of protecting the environment while also strengthening their economies. over the past few decades, the intensified process of urbanization and industrialization undertaken by these countries, coupled with rapid population growth, has resulted in the degradation of the environmental quality. particularl...

a facile and efficient method for the preparation of 1, 1-diacetates of aldehydes is improved.p2o5/sio2 catalyzed 1, 1-diacetates formation from aldehydes in dry media. advantages of this methodare the use of an inexpensive and selective catalyst with high yields in simple operation and shortreaction time under solvent-free conditions.

epilepsy is one of the common neurologic disorders in children. drug side-effects are one of the important problems in treating patients with epilepsy. using the antiepileptic medication may cause different side effects such as disorder in bone and vitamin d metabolism. sodium valproate is one of the antiepileptic medications used widely. some of its side effects include digestive disorder, inc...

chiral pyrrolidines and pyrrolizidines with spirooxindole ring systems are the central skeletons for numerous alkaloids and pharmacologically important compounds. gelesmine, pseudotabersonine, formosanine, isoformosanine, morroniside and mitraphylline are some of the alkaloids containing spirooxindole ring systems. derivatives of spirooxindole find very wide biological applications as anti micr...

introduction: astrocytes are the most abundant glial cell type. in addition to their neurological roles, astrocytes also have immune functions. they have been involved in antigen presentation in the central nervous system (cns). activated astrocytes express adhesion molecules, chemokines and release several inflammatory mediators, pro-inflammatory cytokines, neurotrophic and neuroprotective fac...