Mature beagles were fed a ground-meal diet containing 0, 2, or 10 mug of oxytetracycline per g for 44 days. The 10-mug/g diet resulted in a shift from a predominantly drug-susceptible population of enteric lactose-fermenting organisms to a multiply antibiotic-resistant population which peaked at 78% resistant organisms. Since a shift to drug-resistant organisms did not occur in the group fed 2 ...

The effects of seven antibiotics (streptomycin, amikacin, polymyxin B, lincomycin, clindamycin, tetracycline and oxytetracycline) were compared with those of magnesium, tubocurarine and lignocaine in the frog sciatic nerve--sartorius muscle preparation, using intracellular recording techniques. All compounds except tubocurarine decreased end-plate potential quantal content. The prejunctional ef...

Pigs had a higher degree of gastrointestinal protozoa infection 93 out of 100 faecal samples. Balantidium coli rd infected pigs were controlled effectively by oxytetracycline (100% on 3 day of observation) and Metronidazole th +Furazolidone combination (100% on 5 day of observation). Initially B. coli infected pigs had decreased haemoglobin, pack cell volume and total erythrocyte count values, ...

OBJECTIVE To examine the effectiveness of mass medication with long acting antibiotics at feedlot entry on lot-fed Australian domestic cattle during a period of high risk for bovine respiratory disease (BRD). DESIGN Systematic allocation at feedlot entry of tilmicosin, long acting oxytetracycline or no antibiotic treatment, to cattle lot fed for the Australian domestic market. Comparisons of ...

Eight male cattle were given a combined dose containing 20 mg/kg oxytetracycline and 0.5 mg/kg diclofenac intramuscularly. Blood samples were drawn at different times until 168 h after administration. Two experimental animals were slaughtered by humane means at weekly intervals up to 28 days after administration. Samples of muscle, injection zone tissue, liver, kidney and fat were obtained. Oxy...

135 Abstract: Pharmacokinetics of oxytetracycline were investigated in 20 sheep following intravenous injection of 40, 80 and 160 mg/kg doses. An increase in concentration of oxytetracycline was found with increasing dose at all the sampling times in each animal. The peak plasma concentration of oxytetracycline attained after intravenous administration of 40, 80 and 160 mg/kg of the drug was 18...

The objective of this study was to compare the efficacy of oxytetracycline, enrofloxacin and imidocarb for the elimination of persistent Anaplasma marginale infection in naturally infected Sahiwal cattle. A total of sixty Anaplasma marginale seropositive adult Sahiwal cattle were selected having their ages between 3-4 years ranging in weight from 246-341 kg. The animals were divided in four gro...

The effect of 2 different oxytetracycline treatments in acute E. phagocytophila infected lambs was investigated. Twenty 5-month-old lambs of the Dala and Rygja breeds were used. Ten lambs were inoculated intravenously with a stabilate of an ovine E. phagocytophila strain. On the third day of fever, 4 lambs were given long-acting oxytetracycline (Terramycin prolongatum vet, Pfizer) (20 mg/kg) in...

The in vitro antimicrobial activities of oxolinic acid, flumequine, sarafloxacin, enrofloxacin, and oxytetracycline against strains of bacteria pathogenic to fish (Aeromonas salmonicida subsp. salmonicida, atypical A. salmonicida, Vibrio salmonicida, Vibrio anguillarum, and Yersinia ruckeri) were determined at two different incubation temperatures, 4 and 15 degrees C, by a drug microdilution me...