background & aim: the most common primary brain tumors of the central nervous system are gliomas. among a number of different biomolecular events, a strong relation between oxidative stress pathways and the development of this cancer has been proved. oxidative stress (os) is the consequence of an imbalance between pro-oxidants and antioxidants towards pro-oxidants. the pro-oxidants cause lipid ...

exposure to air pollutants, steel dust or other occupational and environmental hazards as oxidative stress have adverse effects on subway workers' health. oxidative stress generates an excessive amount of reactive oxygen species (ros) and oxygen free radicals during their work time in the tunnels. once dna is repaired, urinary 8-hydroxy-deoxyguanosine (8-ohdg) is excreted in the urine. therefor...

the aim of this study was to assess the effects of eight weeks of continuous running trainingand four weeks of detraining on lipid peroxidation (mda) and anti-oxidative system response after an acute exercise session. for this purpose, 20 sedentary healthy males were randomly divided into two groups: experimental and control. at the beginning, before and after one acute exercise session, blood ...

background: parkinson's disease is one of the prevalent degenerative diseases of the neural system. oxidative stress, which has been recognized as the most important factor of parkinson's disease, plays a main role in the death of neurons in this disease. antioxidants have a proved role in the prevention of oxidative stress. objective: considering the presence of evidence regarding antioxidant ...

objective: oxidative stress is involved in the pathophysiology of diabetes and cardiovascular complications of metabolic syndrome. the main objective of this study was to evaluate total antioxidant status by diphenylpicrylhydrazyl (dpph)-scavenging activity in patients developed metabolic syndrome (mets). materials and methods: forty-four patients with mets diagnosed on the basis of adult treat...

results the level of gsh significantly decreased. in contrast, the plasma level of mda significantly increased in a dose dependent manner in crvi-treated rats, when compared to control animals. simv had no effect on the biochemical parameters when compared to control rats, but significantly increased gsh concentration and decreased mda level in crvi-treated rats. materials and methods sixty-fou...

introduction: toxic effects of pesticides are commonly associated with reactive oxygen species damage and pentoxifylline a phosphodiesterase inhibitor is a drug well known for antioxidant properties. the purpose of this study was to evaluate the oxidative damages following a subacute exposure to malathion, an organophosphorus insecticide and pentoxifylline's ability to counteract these eff...

background: cyclosporine a (csa) is a potent immunosuppressant drug with therapeutic and toxic actions. the use of csa is limited by its toxicity. several researchers had proposed that oxidative stress could play an important role in csa-induced toxicity. arbutin has recently been shown to possess antioxidative and free radical scavenging abilities.the present study was designed to investigate ...