نتایج جستجو برای: oxazolidinone
تعداد نتایج: 557 فیلتر نتایج به سال:
In the title compound, C15H17NO4S2, synthesized by addition of O-ethylxanthic acid potassium salt to a diastereomeric mixture of (4R)-3-(2-chloro-propano-yl)-4-phenyl-oxazolidin-2-one, the oxazolidinone ring has a twist conformation on the C-C bond. The phenyl ring is inclined to the mean plane of the oxazolidinone ring by 76.4 (3)°. In the chain the methine H atom is involved in a C-H⋯S and a ...
A structure-activity relationship (SAR) study on 5-substituted oxazolidinones as an antibacterial agent is described. The oxazolidinones, of which 5-acetylaminomethyl moiety was converted into other functions, were prepared and evaluated for antibacterial activity. Elongation of the methylene chain (8) and conversion of the acetamido moiety into guanidino moiety (12) decreased the antibacterial...
A concise method is reported for the synthesis of 2-aminobicyclo[3.2.0]heptane-2,7-dicarboxylic acid, a close analogue glutamate receptor ligand LY354740, in both enantiomeric forms. The strategy features creation core structure at start via photochemical [2 + 2] cycloaddition reaction, an efficient resolution procedure using chiral oxazolidinone, and requires only minimal purification syntheti...
Oxazolidinone represents a class of most important five-membered cyclic carbamates. They are great significance for modern organic synthesis and widespread as pharmacologically active compounds. This review summarizes recent advances in the chemistry 2-oxazolidinones, with an emphasis on their synthesis, employing different catalytic systems or catalyst-free conditions, well ring-opening transf...
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