UNLABELLED The treatment of otosclerosis is eminently surgical. Good immediate results have been well documented when stapedotomy or stapedectomy are chosen. OBJECTIVES This study aims to assess long term audiometric performance after otosclerosis surgery. MATERIALS AND METHODS this retrospective study enrolled stapedotomy and partial stapedectomy patients seen at our service with proven he...

INTRODUCTION AND OBJECTIVE Stapes replacement surgery performed in cases of otosclerosis alters various anatomical (ossicular, ligament, and tendon) elements of the middle ear affecting their physical properties. The goal of our work is to determine which of the surgical techniques applied during otosclerosis most respects the mechanical-acoustic features of the middle ear. PATIENTS AND METHO...

Patients with superior semicircular canal dehiscence (SSCD) may have conductive hearing loss (CHL) with normal middle ear (ME). A patient with CHL and normal tympanic membrane at otoscopy underwent tympanotomy for presumed otosclerosis but had negative intraoperative findings. A high-resolution computed tomography (CT) scan of the temporal bone performed a few years later showed the absence of ...

OBJECTIVES/HYPOTHESIS To evaluate the long-term (5-year) results of the shape-memory nitinol stapes piston in the surgical treatment of otosclerosis. STUDY DESIGN Retrospective case review in a tertiary referral center. METHODS The patients were adults with clinically proven otosclerosis undergoing stapedotomy. Stapedotomy and ossicular chain reconstruction using a shape-memory nitinol stap...

OBJECTIVE: Otosclerosis surgery is one of the otologic surgeries producing fastest results. It offers crucial advantages such as short operation time, high level satisfaction during postoperative hearing recovery and hospital stay. The purpose otosclerosis to relieve immobility in ossicular chain due disease provide voice transmission again. This study aims evaluate gain rates complications pat...

A 26-year-old woman with bilateral otosclerosis underwent right stapedectomy with an excellent result. One year later, however, she developed symptoms of mumps and within two days was completely deaf in the right ear. Prompt surgical exploration excluded a complication of the otosclerosis and a perilymph fistula, but culture of a sample of perilymph grew mumps virus. The case provides direct ev...

9 TIIVISTELMÄ (FINNISH SUMMARY) 11

Otosclerosis (OTSC) is defined by abnormal bone remodeling in the otic capsule of middle ear which leads to conductive hearing loss. In our previous study, we have identified a de novo heterozygous mutation -832G > A in the promoter of TGFB1 in an otosclerosis patient. In the present study, we progressively screened this mutation in a cohort of 254 cases and 262 controls. The family members of ...

INTRODUCTION Fabry disease is an X-linked lysosomal storage disorder resulting in a multiple-system disorder with a wide spectrum of physical signs and symptoms, predominantly affecting the central and peripheral nervous systems, skin, heart, kidneys, and eyes. CASE PRESENTATION We describe the case of a 26-year-old European Caucasian man who had Fabry disease and who presented with episodic ...