OBJECTIVE The aim of this study was to investigate whether or not radiographic changes observed in knee osteoarthritis (OA) in type 2 diabetes mellitus (T2DM) patients on insulin therapy differed from those not on insulin. MATERIAL AND METHODS A cross-sectional study was performed in 311 subjects: 211 T2DM patients and 100 without diabetes (controls) in Mubarak Hospital, Kuwait. Patients were...

OBJECTIVE Various procedures have been introduced for anterior interbody fusion in degenerative cervical disc disease including plate systems with autologous iliac bone, carbon cages, and cylindrical cages. However, except for plate systems, the long-term results of other methods have not been established. In the present study, we evaluated radiologic findings for cylindrical cervical cages ove...

The initiation of cartilage degeneration has been linked to the onset of subchondral bone remodelling and osteophyte formation at the cartilage-bone interface. As such, Osteoarthritis (OA) is defined as the thinning of cartilage and/or osteophyte formation. Cartilage adjacent to healthy bone has a characteristic stress distribution when loaded within a healthy range. This loading is then transf...

STUDY DESIGN A 12-year prospective study of de novo scoliosis in a community based cohort. OBJECTIVE.: To investigate factors associated with development of de novo scoliosis. SUMMARY OF BACKGROUND DATA De novo scoliosis is becoming one of the most prevalent findings in the aging spine, and this condition is associated not only with severe back or leg symptoms but also with complicated surgic...

INTRODUCTION Triamcinolone acetonide (TA) is used for osteoarthritis management to reduce pain, and pre-clinical studies have shown that TA limits osteophyte formation. Osteophyte formation is known to be facilitated by synovial macrophage activation. TA injections might influence macrophage activation and subsequently reduce osteophytosis. Although widely applied in clinical care, the mechanis...

BACKGROUND Osteoarthritis (OA) involves cartilage changes as well as modifications of subchondral bone and synovial tissues. Strontium ranelate (SR), an anti-osteoporosis compound, which is currently in phase III clinical trial for treatment of OA. Evidences suggest that SR preferably deposited in osteophyte, other than in subchondral bone in early phase of OA. This phenomenon raises concern ab...

A spine x-ray image retrieval system has been developed for retrieving images based on the pathology information such as the osteophyte. Osteophyte shows only in particular regions on the vertebra. This means the contour information on the vertebra regions that are not of interest hinder the image retrieval relevance precision. Curve matching or partial shape matching (PSM) methods based on dyn...