Hydroxyapatite (HAp), a main constituent of the cortical bone, retains large surface charge that plays critical role in regeneration bones, whose source remains an enigma. Here, we used multi-eigenmode piezoresponse force microscopy via Pearson correlation and conducted multiscale material analysis to independently measure piezoelectric coefficient density HAp. Quantitative comparison was betwe...

Among the options for femoral reconstruction in total hip arthroplasty (THA) revision procedures, in cases of extensive circumferential defects, is the use of proximal femoral allografts. This technique makes it possible to correct the hip abductor mechanism and the leg length discrepancy, as well as presenting osteoconductive potential. The authors report the clinical and radiographic results ...

Bioactive glass-ceramic nanoparticles (nBGC) may be produced using sol-gel methodologies. These nanobiomaterials may be used in a series of biomedical applications, such as tissue engineering of mineralised tissues. The preparation of nBGC and their properties are resumed. Example os applicability of nBGC in the orthopaedic field are presented, including in the preparation of scaffolds based on...

Autogenous bone is regarded as the gold standard for bone graft materials as it provides 3 elements necessary to generate and maintain bone: scaffolding for osteoconduction, growth factors for osteoinduction, and progenitor cells for osteogenesis. Allograft is more limited than autograft in these essential elements and yields more variable clinical results. Composite synthetic grafts offer an a...

This aim of this research was to develop a novel ceramic scaffold to evaluate the response of bone after ceramic implantation in New Zealand (NZ) rabbits. Ceramics were prepared by the polymer replication method and inserted into NZ rabbits. Macroporous scaffolds with interconnected round-shaped pores (0.5-1.5 mm = were prepared). The scaffold acted as a physical support where cells with osteob...