نتایج جستجو برای: osteoblast response

تعداد نتایج: 984412  

Journal: :Journal of immunology 2008
Ming K Chang Liza-Jane Raggatt Kylie A Alexander Julia S Kuliwaba Nicola L Fazzalari Kate Schroder Erin R Maylin Vera M Ripoll David A Hume Allison R Pettit

Resident macrophages are an integral component of many tissues and are important in homeostasis and repair. This study examines the contribution of resident tissue macrophages to bone physiology. Using immunohistochemistry, we showed that a discrete population of resident macrophages, OsteoMacs, was intercalated throughout murine and human osteal tissues. OsteoMacs were distributed among other ...

2013
Paul D. H. Prowse Christopher G. Elliott Jeff Hutter Douglas W. Hamilton

Reducing the time required for initial integration of bone-contacting implants with host tissues would be of great clinical significance. Changes in osteoblast adhesion formation and reorganization of the F-actin cytoskeleton in response to altered topography are known to be upstream of osteoblast differentiation, and these processes are regulated by the Rho GTPases. Rac and RhoA (through Rho K...

Journal: :Biochemical and Biophysical Research Communications 2014

Journal: :BoneKEy reports 2015
Rafik Mansouri Eric Haÿ Pierre J Marie Dominique Modrowski

Syndecans 1-4 are a family of transmembrane proteins composed of a core protein and glycosaminoglycan chains. Although the four syndecans have common functions, they appear to be connected to different signaling pathways, and their expression occurs in a cell- and development-specific pattern. In contrast to other syndecans, syndecan-2 expression increases during osteoblast differentiation. Mec...

2013
S. Sarkar R. Mahapatra A. E. Sowers C. A. Jorda L. M. Mir F. Bureau J. Gehl R. Rangara D. Rouy J. M. Caillaud P. Delaere G. Sersa T. Cufer M. Cemazar M. Rebersek S. B. Dev D. P. Rabussay G. Widera G. A. Hoffmann

We report the computational simulation study for the characterization of multilayer dense osteoblast intra organelle membrane potential in different microelectrode. The response of a cell model at various frequencies and the effect of cell parameters, such as cell membrane resistance and capacitance, were studied. We show that at low frequencies—the intra organelle can be electro porated while ...

Journal: :iranian journal of medical sciences 0
naser abbasi department of pharmacology, school of medicine, iran university of medical sciences, tehran, iran afra khosravi biotechnology and medicinal plants research center, ilam university of medical sciences, ilam, iran ali aidy biotechnology and medicinal plants research center, ilam university of medical sciences, ilam, iran massoumeh shafiei department of pharmacology, school of medicine, iran university of medical sciences, tehran, iran

background: clinical evidence indicates the diabetes-induced impairment of osteogenesis caused by a decrease in osteoblast activity. flavonoids can increase the differentiation and mineralization of osteoblasts in a high-glucose state. however, some flavonoids such as luteolin may have the potential to induce cytotoxicity in osteoblast-like cells. this study was performed to investigate whether...

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