UNLABELLED The sixth Osteoarthritis Research Society International (OARSI) Workshop on Imaging in Osteoarthritis combined with the third osteoarthritis (OA) Biomarkers Workshop is the first to bring together the imaging and molecular biomarker communities to focus on clinical validation and qualification of OA biomarkers. The workshop was held in Hilton Head, SC, USA, from June 12-14, 2012; 138...

Purpose: To investigate the patterns of dispensed opioids, NSAIDs, physiotherapy (PT) visits, as well primary care and specialist visits for musculoskeletal complaints other than osteoarthritis (OA), in patients with OA who do, do not, undergo knee replacement (KR).

Introduction Osteoarthritis (OA) is the most common form of degenerative joint disease characterized by progressive degeneration articular cartilage, osteophyte formation, and space narrowing. Matrix metalloproteinases (MMPs) are potential biomarkers for osteoarthritis. Aims objective The study's aim estimation serum synovial fluid matrix metalloproteinase (MMP) 13 vitamin D levels in grade 3 4...

Osteoarthritis is the most common human arthritis characterized by degeneration of articular cartilage. Several studies reported that levels of human cartilage glycoprotein chitinase 3-like-1 (CHI3L1) are known as a potential marker for the activation of chondrocytes and the progression of Osteoarthritis (OA), whereas lubricin appears to be chondroprotective. The aim of this study was to invest...

Objective(s): The aim of the present research is to investigate the efficacy of L-carnitine (LC) as a complementary therapy to diclofenac sodium (Dic) treatment in a mono-iodoacetate (MIA) induced knee osteoarthritis (OA) rat model, with respect to pain relief and the underlying pathology.Materials and Methods: Fifty adult male albino ra...

BACKGROUND The aim of this study was to evaluate the role of interleukin-17 (IL-17) level in synovia and its relationship with the severity of knee osteoarthritis (OA). MATERIAL AND METHODS We enrolled 226 OA patients and 106 controls in this study. The symptomatic/radiation severity of OA was assessed by the Western Ontario McMaster University Osteoarthritis Index (WOMAC) pain score/Kellgren...

Objective: To comment on and explore (1) the prevalence of clinical knee hip osteoarthritis (OA); (2) association between pain or function OA; (3) injury surgery OA. Methods: Participants were recruited from FIFPRO members. A total 101 footballers consented to answer a developed questionnaire, patient-reported outcome measures, be evaluated by their team physician for Results: Of 53% OA, 9.43% ...

Introduction: Osteoarthritis (OA) is estimated to be the eleventh leading cause of disability worldwide. In Asian countries, OA is much less well-known than in the caucasian population and strongly associated with aging. Therefore, this article focuses comprehensively on the prevalence, risk factors and primary prevention for OA identified in Asian countries.   Methods: This scoping review us...

Osteoarthritis (OA) is a progressive multifactorial disease that not only leads to articular cartilage loss and joint space narrowing, but also to pain, loss of function and physical disability, thus greatly impairing quality of life. The concept of the pathology of OA has evolved from being viewed as cartilage-limited to a multifactorial disease affecting the whole joint. Indeed, all the joint...

INTRODUCTION This study investigated the effectiveness of extracorporeal shockwave therapy (ESWT) in osteoporotic (OP) osteoarthritis (OA) of rat knee. METHODS Fifty-six rats were divided into seven groups including sham, OA, OP, OA + OP, OA + ESWT, OP + ESWT, and OA + OP + ESWT groups. The evaluations included gross pathology, bone mineral density (BMD), micro-computed tomography (micro-CT) ...