The physis or epiphyseal plate is where future bone is laid down and is constantly changing during the years of growth. The relative weakness at the physis and decreased resistance to shear and tensile forces compared to the surrounding ligaments, tendons and muscles predisposes this area to potential injury [1-3]. Therefore, it is important to take into account the maturation of the bone inclu...

Developmental variations in the cranial vault arise during early ontogenesis due to premature or delayed suture closure, non-union between normal ossification centers, and emergence of additional centers. These cause abnormal calvarial partition are often associated with modifications overall configuration. This study aims evaluate impact metopic persistence development supernumerary bones occi...

OBJECTIVE The epiphyses ossification centers appear late in gestation, when traditional biometric measurements are the least accurate, and they can be useful in determining third trimesters gestational age. To evaluate fetal distal femoral epiphysis (DFE) size in various ages of gestation and establish a reference chart for Iranian population. MATERIALS & METHODS DFE diameter was measured in ...

Cartilage canals (CCs) are microscopic structures involved in secondary ossification centers (SOCs) development. The features of CCs were investigated in the humeral and femoral proximal epiphyses of small-sized newborn dogs (from premature to 28 days after birth) with histochemical and immunohistochemical approaches. Masson's Trichrome revealed a ring-shaped area around CCs, which changes in c...

Purpose : Ossification of the laryngeal cartilage has been investigated, including pattern ossification, age-related changes, and sex differences. This study aimed to examine beginning, processes, differences ossification in Japanese patients using ultra-high-resolution computed tomography (UHRCT).

Case Description- A three month Holstein female calf with a supernumerary limb in the caudal cervical region was delivered to a private veterinary clinic in Kashmar.Clinical Findings- Clinical and radiographical examinations revealed a vestigial scapula, distally bifurcated humerus, two underdeveloped ulnae, two ossification centers for radius and more or less complete duplication of manus in t...

Objective To evaluate the age in which the secondary ossification centers of the elbow appear and fuse in the Brazilian population. Methods Nearly thirty radiographs were randomly selected for each age group from 0 to 18 years, with a total of 544 radiographs from 439 patients, between 2010 and 2015, without abnormalities secondary to trauma, metabolic or bone tumor diseases. Radiographs were...

Activating mutations in FGFR3 cause achondroplasia and thanatophoric dysplasia, the most common human skeletal dysplasias. In these disorders, spinal canal and foramen magnum stenosis can cause serious neurologic complications. Here, we provide evidence that FGFR3 and MAPK signaling in chondrocytes promote synchondrosis closure and fusion of ossification centers. We observed premature synchondr...

The wrist and hand region has been the most commonly used for estimating age and osseous development due to the great number of ossification centers. The aim was to determine which method, Tanner & Whitehouse's (TW3), Greulich & Pyle's (GP) or Eklof & Ringertz's, more closely relates to the chronological age in subjects with Down syndrome with chronological ages between 61 and 180 months, using...