In this research, frictions stir welding of aluminum alloy AA2024 and with its similar plate having a cross section 100 x 50 5 mm. The work piece is heating variation temperature holding time cooled it in water. Heat treated work-piece welded by friction process tool rotation speed other parameters are constant for all experiment. For experiment design using the selected control Temperature, th...

Objective Osteoarthritis (OA) affects humans and several other animals. Thus, the mechanisms underlying this disorder, such as specific skeletal tissue DNA methylation patterns, may be evolutionary conserved. However, associations between methylation and OA have not been readily studied in nonhuman animals. Baboons serve as important models of disease and develop OA at rates similar to those in...

OBJECTIVES In osteoarthritis (OA), the balance between catabolic and anabolic mediators and their regulators in cartilage is disturbed. Proinflammatory cytokine interleukin-1 (IL-1) plays a central role in cartilage destruction and nitric oxide (NO) mediates many of its destructive effects. In the present study, we investigated the secretion of 40 mediators related to inflammation or cartilage ...

This paper espouses the application of orthogonal array experiment to solve a class of engineering optimization problems encountered in systems engineering and architecting. It also illustrates the applicability of orthogonal array experiment in systems engineering and architecting with two examples: verification and validation of the performance of a bandwidth allocation algorithm and architec...

The potential role of PFD [5-methyl-L-phenyl-2-(1H)-pyridone], an antifibrotic compound with anti-inflammatory effects, in several models of acute lung injury (ALI) has gained increasing attention; however, the protective effect of PFD in oleic acid (OA)-induced ALI remains unknown. We hypothesized that PFD protects from OA-induced ALI in rats, and we hoped to obtain the optimum preclinical con...

The Mahalanobis-Taguchi System (MTS) is a data mining method employing Mahalanobis distance (MD) and Taguchi′s Robust Engineering philosophy to explore and exploit data in a multidimensional system. The MD calculation provides a measurement scale to discriminate sample data and gives an approach of measuring the level of severity among them. One unique feature of MTS lies its robustness to asse...

this work presents an experimental investigation of the influence of the six important machining parameters (tool nose radius, tool rake angle, feed rate, cutting speed, cutting environment (dry, wet and cooled) and depth of cut) on surface roughness & material removal rate in the machining unidirectional glass fiber reinforced plastics (ud-gfrp) composite using carbide (k10) cutting tool durin...

To investigate the material removal characteristic of paste polishing, experimental investigations based on Taguchi method have been carried out. In the experiments, the dwell time was fixed 300 seconds and the bonnet position was 4. The four variable factors (precess angles, head speed, head pressure and tool offset) with 3 levels were chosen to design the orthogonal array. With the designed o...

We extend the notions of correlation-immune functions and resilient functions to functions over any nite alphabet endowed with the structure of an Abelian group. Thus we generalize the results of Gopalakrishnan and Stinson as we give an orthogonal array characterization and a Fourier transform characterization for resilient functions over any nite alphabet. This leads to a generalization of som...

Machining of medium Brass alloy is very difficult. There are a number of parameters like cutting speed, feed and depth of cut etc. which must be given consideration during the machining of medium Brass alloy. This study investigates the effects of process parameters on Material Removal Rate (MRR) in turning of C34000. The single response optimization problems i.e. optimization of MRR is solved ...