Organophosphate resistant and susceptible populations of the western corn rootworm, Diabrotica virgifera virgifera LeConte. were subjected to adult feeding bioassays with different combinations of insecticide and a cucurbitacin bait. Five technical grade insecticides (methyl-parathion, carbaryl, fipronil, bifenthrin and indoxacarb) were used in combination with Invite ECt as the feeding stimula...

Insecticide resistance has been known to be prevalent in several insect species including mosquito. It has become a major problem in vector control programme due to pesticide resistance through detoxification enzymes. The present study investigated the toxicity of Ae. aegypti to organophosphates and pyrethroid insecticide and biochemical mechanisms involved in insecticide resistance in larval p...

Phosphamidon, a systemic organophosphate insecticide, (1.4 mg/kg - dose 1/4th of LD50 given ip), produced several autonomic, neurological and behavioral effects in mice with peak effects being at 15 min. Similar dose in rats also abolished conditioned avoidance response. Pre-treatment with atropine, iproniazid, alpha-methyl-p-tyrosine, p-chlorophenylalanine or thiosemicarbazide reduce many of t...

Malathion (see Figure 1) is an insecticide in the organophosphate chemical family. It is one of the oldest insecticides in that family, and has been used since 1950. Cheminova, Inc. is the major U.S. manufacturer of malathion.1 “Safe”1 is a term often used to describe malathion, as are phrases such as “with proper precautions, problems should be minimal.”2 However, recent research shows that ma...

We report a case of organophosphate poisoning presenting as a cardiac arrest. The diagnosis was delayed due to the absence of a history of insecticide ingestion and the unusually acute presentation. Cardiac arrest with bradycardia poorly responsive to adrenaline and responsive to high dose atropine should alert the clinician to the possibility of an anticholinesterase poisoning. Early diagnosis...