Oral cancer accounts for the majority of the cancer in South East Asian region and especially in the Indian subcontinent. If diagnosed at an early stage the disease is reported to have a better prognosis. Sialochemistry involving antioxidants has recently gained importance for oral cancer risk assessment because of its non-invasive nature. The aim of this study was to estimate the levels of glu...

Oral cancer accounts for the majority of the cancer in South East Asian region and especially in the Indian subcontinent. If diagnosed at an early stage the disease is reported to have a better prognosis. Recently studies have been conducted to determine the levels of serum antioxidants for risk assessment of oral cancer. The aim of this study was to estimate the levels of glutathione in serum ...

Present study was undertaken to estimate and compare erythrocyte superoxide dismutase (E-SOD) and Glutathione peroxidase (GPx) levels in oral submucous fibrosis, oral leukoplakia and oral cancer patients and age/sex matched healthy subjects, 25 in each group. Statistically significant (P<0.001) decrease in E-SOD and GPx levels were observed in OSF, oral leukoplakia and oral cancer groups as com...

AIM To determine the prevalence of oral lesions in a HIV+ group of patients, related to CD4 cell count and viral load in a Venezuelan population. MATERIALS AND METHODS In the present study, we evaluated 75 HIV+ adult patients, attended at the Center of Infectious Diseases, at the Faculty of Dentistry, Central University of Venezuela. Each patient was clinically examined for detection of oral ...

Background. Oral squamous cell carcinoma is the sixth most frequent malignant tumor worldwide and the third most common cancers in developing countries. Oral leukoplakia is the best-known precursor lesion of oral squamous cell carcinoma. The aim of the present study was to compare immunohistochemical expression of antiapoptotic protein survivin in normal oral mucosa, oral leukoplakia, and oral ...

Definition Leukoplakia is the most common premalignant or "potentially malignant" lesion of the oral mucosa. Leukoplakia is a predominantly white lesion of the oral mucosa than cannot be clinicopathologically characterized as any other definable lesion. The term leukoplakia is a clinical descriptor only and should not be used once histological information is available. On the other hand, the te...

The aim of the present study was to evaluate the definition of oral leukoplakia, proposed by the WHO in 2005 and taking into account a previously reported classification and staging system, including the use of a Certainty factor of four levels with which the diagnosis of leukoplakia can be established. In the period 1997-2012 a hospital-based population of 275 consecutive patients with a provi...

OBJECTIVES The aim of this study was to diagnosis oral lesions related to HIV infection in individuals followed in the General Hospital of the School of Medicine of Ribeirão Preto, University of São Paulo, Brazil. The presence of oral lesions was correlated with gender, age, smoking habit, levels of CD4 lymphocytes, HIV load, time of HIV seropositivity, AIDS condition, use of removable dental p...

O Ox xi id da an nt ts s a an nd d A An nt ti io ox xi id da an nt ts s i in n M Me ed di ic ca al l S Sc ci ie en nc ce e available at www.scopemed.org Abstract In the SouthEast Asian countries oral cancer is one among the commonly occurring malignancies due to tobacco use and quid chewing habits. Early stage diagnosis of the disease is reported to have a better prognosis. Sialochemistry studi...

INTRODUCTION Proliferative verrucous leukoplakia is a multifocal and progressive lesion of the oral mucosa, with unknown etiology, and commonly resistant to all therapy attempts with frequent recurrences. It is characterized by a high rate of oral squamous cell carcinoma and verrucou carcinoma transformations. OBJECTIVE To analyze the studies about Proliferative verrucous leukoplakia and deve...