we evaluated the ability of spectral-domain optic coherence tomography (sd-oct) to differentiate large physiological optic disc cupping (lpc) from glaucomatous cupping in eyes with intraocular pressure (iop) within the normal range.â  we prospectively enrolled patients with glaucoma or presumed lpc. participants â had optic discs with confirmed or suspected glaucomatous damage (defined as a ver...

Optical coherence tomography (OCT) is considered a key research tool to monitor neurodegenerative processes in CNS disorders. This particularly applicable multiple sclerosis (MS), which retinal changes (peripapillary nerve fiber layer and ganglion cell–inner plexiform [GCIPL] thicknesses) tend reflect MRI markers of damage atrophy, especially eyes not affected by previous optic neuritis.1

Following an episode of optic neuritis, thinning of the retinal nerve fibre layer, which indicates axonal loss, is observed using optical coherence tomography. The longitudinal course of the retinal changes has not been well characterized. We performed a serial optical coherence tomography study in patients presenting with optic neuritis in order to define the temporal evolution of retinal nerv...

Purpose: Evaluation of ganglion cell complex measurement and the use parameters lamina cribrosa depth in early diagnosis progression patients with suspected glaucoma.
 Materials Methods: Measurements were taken Heidelberg Spectralis Spectral Domain Optical Coherence Tomography from both groups. Ganglion thicknesses measured segmentation analysis. Lamina depths by using optic nerve head ima...

Post-mortem ganglion cell dropout has been observed in multiple sclerosis; however, longitudinal in vivo assessment of retinal neuronal layers following acute optic neuritis remains largely unexplored. Peripapillary retinal nerve fibre layer thickness, measured by optical coherence tomography, has been proposed as an outcome measure in studies of neuroprotective agents in multiple sclerosis, ye...

OBJECTIVES To evaluate the incidence of chorioretinal anastomosis after radial optic neurotomy and to determine its effect on visual acuity and foveal thickness in patients with central retinal vein occlusion. METHODS We conducted a prospective, uncontrolled, interventional study of 14 patients with preoperative visual acuities below 20/125. Pars plana vitrectomy and radial optic neurotomy we...

Optical coherence tomography has evolved over the past 2 decades to be an important ancillary method to evaluate diseases of the anterior and posterior segments of the eye. The more recent development of swept-source optical coherence tomography (SS-OCT) with a wavelength-tunable laser centered at 1050 nm and deeper imaging depth of 2.6 mm has enabled clinicians to evaluate congenital optic dis...

Optic disc drusen (ODD) are benign congenital anomalies of the optic nerve characterized by calcified hyaline bodies. While superficial drusen can be diagnosed easily during fundus examination, detecting buried drusen requires the use of additional imaging methods such as B-scan ultrasonography (USG), fundus fluorescein angiography (FFA), computed tomography (CT) and fundus autofluorescence (FA...