AIMS To test the hypothesis that in patients with acquired chronic bilateral ophthalmoplegia, abnormal retinal image slippage during head movements would result in abnormal thresholds for visual perception of motion. METHODS Five patients (two males and three females) with ophthalmoplegia were included in the study. The average age was 44 years (range 30-69 years). The aetiology of ophthalmop...

Two patients presented with a supranuclear ophthalmoplegia and clinical features otherwise indistinguishable from classical Parkinson's disease. Both had intercurrent infection, and recovery from the ophthalmoplegia paralleled that from the infection, but the Parkinsonian features improved more gradually on increasing doses of levodopa.

A left ophthalmoplegia and right hemiplegia were due to thrombosis of an intracavernous aneurysm with occlusion of the left internal carotid artery. Ophthalmoplegia with contralateral hemiplegia is probably a rare syndrome. Thrombosis of an intracavernous aneurysm is probably a rare cause of occlusion of the internal carotid artery.

Synonyms: MmD, Multi-minicore disease, Minicore myopathy, Multicore myopathy, Multiminicore myopathy, Minicore myopathy with hand involvement, antenatal onset minicore myopathy with arthrogryposis, Minicore myopathy with external ophthalmoplegia, Multicore myopathy with external ophthalmoplegia, Multiminicore disease with external opthalmoplegia, SEPN1-related congenital muscular dystrophy, rig...

CONTEXT Machado-Joseph disease (MJD), an autosomal dominant spinocerebellar degeneration caused by an expanded CAG repeat on chromosome 14q32.1, is a heterogeneous disorder for clinical manifestations. The reasons for the wide range of neurologic findings in this disease are poorly understood. OBJECTIVE To explain part of this heterogeneity through the association of the neurologic findings w...

IgG anti-GQ1b antibody was present in a patient with acute ataxia and areflexia without ophthalmoplegia or elementary sensory loss. Sensory nerve conduction studies and somatosensory evoked potentials were normal, but postural body sway analysis showed dysfunction of the proprioceptive afferent system. The clinical presentation and laboratory results for this patient resemble those of Miller Fi...

PURPOSE To report a case of pure isolated unilateral internuclear ophthalmoplegia from ischemic stroke, and to review its literature. METHODS A 55-year old man, with a history of long-standing diabetes mellitus, developed acute-onset left internuclear ophthalmoplegia. MRI revealed a small paramedian dorsal pontine infarct ventral and lateral to the aquaductus cerebri. Intracranial MR angiogra...

A 40-year-old female after a closed head injury presented with bilateral internuclear ophthalmoplegia. Attempted convergence was abnormal and MRI revealed the focal hemorrhage in the medial longitudinal fasciculus region by showing bright signal in the a pontomesencephalic region in the midline on both T1 and T2 weighted images. The patient regained normal ocular mobility after six months of th...