We have reduced the minimum bending radius of a silica waveguide from 2 mm to 200 μm by burying low-refractive index material along both sides of the core. The local lateral relative refractive index difference (Δ) was increased to 9.05%. Moreover, we fabricated both an 8-channel, 100-GHz channel-spacing arrayed-waveguide grating (AWG) and an 8-channel, 12.5-GHz channel-spacing AWG using variat...

This paper applies an evolutionary algorithm, the particle swarm optimization (PSO), to design the optimum open channel section. Depth, channel side slope and bottom width are considered as the variables for rectangular, triangular and trapezoidal channels, respectively. The objective function is minimizing the construction cost of the channel section. MATLAB software is used for programming an...

[1] The paper investigates the influence of relative bend curvature on secondary flow, energy losses, and turbulence in sharp open-channel bends. These processes are important in natural streams with respect to sediment transport, the bathymetry and planimetry, mixing and spreading of pollutants, heat, oxygen, nutrients and biological species, and the conveyance capacity. Laboratory experiments...

Cardiac sodium channels are integral membrane proteins whose structure is not known at atomic level yet and their molecular kinetics is still being studied through mathematical modeling. This study has focused on adapting an existing model of cardiac Na channel to analyze molecular kinetics of channels at 9-37°C. Irvine et al developed a Markov model for Na channel using Neuronal Network Model ...

Cardiac sodium channels are integral membrane proteins whose structure is not known at atomic level yet and their molecular kinetics is still being studied through mathematical modeling. This study has focused on adapting an existing model of cardiac Na channel to analyze molecular kinetics of channels at 9-37°C. Irvine et al developed a Markov model for Na channel using Neuronal Network Model ...

secondary flow investigation could be regarded as an important issue in open channel flow, in spite of its lower quantity compared to the base flow in the water course. it should be given special consideration because of the influence on some hydraulic factors in open channel, specifically in compound channels. in compound channels' due to the difference in the flow velocity of the main ch...

The nicotinic acetylcholine (ACh) receptor converts transiently to an open-channel form when activated by ACh released into the synaptic cleft. We describe here the conformational change underlying this event, determined by electron microscopy of ACh-sprayed and freeze-trapped postsynaptic membranes. ACh binding to the α subunits triggers a concerted rearrangement in the ligand-binding domain, ...

Introduction Numerous studies have demonstrated the presence of potassium selective channels in membranes internal organelles. These channels are essential to a large variety of cellular processes including intracellular 2+ a signaling, protein recycling, charge neutralization and cell protection. In contrast to the sarcoplasmic reticulum + here potassium channels have been clearly ...

the developing turbulent flow in an open channel is a complex three-dimensional flow influenced by the secondary currents and free surface effects and is, therefore, not amenable to analytical solution. this paper aims to study the impact of three key hydraulic parameters (relative roughness, the froude number and the reynolds number) on the establishment length using computational fluid dynami...