OBJECTIVE To compare the outcomes of luteal phase support by micronized progesteron vaginal capsule 600mg/day and progesterone vaginal gel 180mg/day in the normoresponder IVF/ICSI-ET cycles of the patients down-regulated via GnRH agonist long protocol or fixed antagonist protocol below 40 years of age. METHODS A total of 463 normoresponder cycles between January 2013 and December 2013 were re...

Early determination of pregnancy viability is essential for women at risk for experiencing ectopic pregnancy or spontaneous abortion. Several markers of pregnancy viability have been identified including serial human chorionic gonadotropin (hCG) monitoring and sonography, in addition to several less commonly available biochemical markers. An ideal test would be readily available, inexpensive an...

BACKGROUND Recent advancement of minimum volume vitrification methods has resulted in a dramatic increase in the efficiency of the process. The aim of this study was to estimate the cumulative reproductive outcome of a cohort of infertile couples undergoing ICSI and oocyte vitrification in restrictive legal conditions, where only a limited number of oocytes could be inseminated per cycle and em...

OBJECTIVE To report the outcomes of more than 100 cycles of preimplantation genetic diagnosis for monogenetic diseases. DESIGN Case series. SETTING Tertiary assisted reproductive centre in Hong Kong, where patients needed to pay for the cost of preimplantation genetic diagnosis on top of standard in-vitro fertilisation charges. PATIENTS Patients undergoing preimplantation genetic diagnosi...

BACKGROUND Race and ethnicity are one of the newly investigated patient-related prognostic factors that might affect the outcome of assisted reproduction techniques. To our knowledge no data currently are available on the effect of race on oocyte donation outcome. MATERIALS A retrospective, matched cohort study was performed in a private infertility centre evaluating 1012 Black, South-East As...

STUDY QUESTION Is the ovarian response to controlled ovarian stimulation (COS) related to the ongoing pregnancy rate when taking into account the main covariates affecting the probabilities of pregnancy following fresh embryo transfer? SUMMARY ANSWER In patients treated with corifollitropin alfa or daily recombinant FSH (rFSH) in a GnRH-antagonist protocol, a high ovarian response did not com...

A previous randomized clinical trial compared immobilization for 15 min with immediate mobilization subsequent to intrauterine insemination (IUI) and showed higher ongoing pregnancy rates in couples immobilizing subsequent to IUI. The current study compared the long-term effectiveness of immobilization subsequent to IUI. All couples (n = 391) included in the trial were followed for 3 years afte...

OBJECTIVE To evaluate the predictive value of the progesterone level at the beta-human chorionic gonadotropin (β-hCG) check day for ongoing pregnancy maintenance in in vitro fertilization (IVF) cycles in women with previous unexplained repeated miscarriages. MATERIALS AND METHODS One hundred and forty-eight women, with visible gestational sac after IVF, were recruited in this observational st...

background: repeated implantation failure (rif) is a major challenge in reproductive medicine and despite several methods that have been described for management, there is little consensus on the most effective one. objective: this study was conducted to evaluate the effectiveness of platelet-rich plasma in improvement of pregnancy rate in rif patients. materials and methods: twenty women with ...