conclusions overall, we found that obi was rare, but that the prevalence of obi was slightly higher in jiangsu than in other areas of china. methods all donor samples were routinely screened by double enzyme-linked immunosorbent assay (elisa) for hepatitis c virus (hcv), hepatitis b virus (hbv), human immunodeficiency virus (hiv), treponema pallidum (tp), and alanine aminotransferase (alt). sin...

A persistent form of the hepatitis B virus called occult chronic hepatitis B has recently been described. Its prevalence and physiopathology are unknown. The aim of this study was to evaluate the occurrence of this clinical entity among patients in the Brazilian Amazon region. Out of 51 anti-HBc total-positive patients who were tested using the polymerase chain reaction, 17% were positive. We d...

Occult hepatitis B virus (HBV) infection is defined as the detection of HBV deoxyribonucleic acid (DNA) in the serum or liver tissue of individuals who test negative for hepatitis B surface antigen (HBsAg). We undertook a prospective study to evaluate the significance and course of occult HBV in patients with hepatitis C virus (HCV) cirrhosis undergoing orthotopic liver transplantation (OLT). A...

We greatly enjoyed reading the excellent review by Hollinger and colleagues on occult hepatitis B infection in chronic hemodialysis (HD) patients (1). As Hollinger et al. mentioned in their review, few studies have shown the prevalence of occult hepatitis B virus (HBV) infection in HD patients. Due to the parenteral transmission of HBV, HD patients are at high risk of acquiring this virus becau...

occult hepatitis b (ohb), or persistent hepatitis b virus (hbv) viremia in surface-antigen-hbsag-negative patients, has been recognized as a medical concern during the last decade. the exact magnitude, pathogenesis and clinical relevance of ohb are unclear. this review organizes the published data on ohb and presents an overview of the current hypotheses on ohb's pathogenesis and clinical relev...

background: in patients who are hepatitis b virus (hbv) dna-positive, but hbv surface antigen (hbsag) -negative, the infection is referred to as occult hepatitis b infection (obi). occult hbv infection is harmful when other liver diseases are present, and can aggravate liver damage in in patients with chronic liver diseases. in human immunodeficiency virus (hiv) infection the suppression of vir...

Chronic hepatitis C virus (HCV) infection combined with occult hepatitis B virus (HBV) infection has been associated with increased risk of hepatitis, cirrhosis and hepatocellular carcinoma. This study aimed to determine the prevalence of occult HBV infection among Egyptian chronic HCV patients, the genotype and occurrence of surface gene mutations of HBV and the impact of co-infection on early...

diagnosis of hepatitis b is routinely based on of serological assay of hepatitis b surface antigen (hbsag). occult hepatitis b virus (hbv) infection is generally defined as the detection of hbv -dna in the serum or tissues of subjects who have negative test for hbsag. transmission of hbv infection has been documented from hbsag negative, anti-hbc positive blood and organ donors. the aim of this...