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INTRODUCTION Hypomelanotic skin disorders like tuberous sclerosis and hypomelanosis of Ito that present with multiple systemic manifestations have been reported in association with childhood autism. Oculocutaneous albinism is another hypomelanotic skin disorder that rarely presents with multiple systemic manifestations. It is infrequently reported in association with childhood autism when compa...

Albinism in plants is characterized by partial or complete loss of chlorophyll pigments and incomplete differentiation chloroplast membranes. This a very common problem encountered interspecific crosses tissue culture experiments including anther generation doubled haploids. impairs photosynthesis the eventually die at young stage without reaching maturity. Environmental conditions such as ligh...

BACKGROUND Oculocutaneous albinism (OCA) is the most common inherited disorder in Southern African blacks and several types have been described. Molecular techniques, where available, can be used to confirm a clinical diagnosis and the type of OCA, if necessary, and for prenatal diagnosis. OBJECTIVES To investigate and classify the different types of albinism commonly found and to determine t...

OCULAR albinism is a form of incomplete albinism in which the lack of pigment is chiefly confined to the eyes. The condition is relatively rare, but since it was described for the first time by Nettleship (1909), it has occasionally been demonstrated in various families. Nettleship was aware that the disease-producing gene was sex-linked, but assumed it to be recessive; recent investigations ha...

Albinism is a rare genetic condition globally characterized by a number of specific deficits in the visual system, resulting in poor vision, in association with a variable hypopigmentation phenotype. This lack or reduction in pigment might affect the eyes, skin, and hair (oculocutaneous albinism, OCA), or only the eyes (ocular albinism, OA). In addition, there are several syndromic forms of alb...

A Chinese girl with oculocutaneous albinism has the Prader-Willi syndrome and a normal karyotype. This association emphasises the importance of further molecular study of the 15(q12) region of the genome in the search for the locus of an albinism gene.

In albinism, the number of ipsilaterally projecting retinal ganglion cells (RGCs) is significantly reduced. The retina and optic chiasm have been proposed as candidate sites for misrouting. Since a correlation between the number of lateral geniculate nucleus (LGN) relay neurons and LGN size has been shown, and based on previously reported reductions in LGN volumes in human albinism, we suggest ...

OCULAR albinism is a form of incomplete albinism in which the lack of pigment is chiefly confined to the eyes. The condition is relatively rare, but since it was described for the first time by Nettleship (1909), it has occasionally been demonstrated in various families. Nettleship was aware that the disease-producing gene was sex-linked, but assumed it to be recessive; recent investigations ha...