The lipid composition of cellular membranes is regulated to maintain membrane fluidity. A key enzyme involved in this process is the membrane-bound stearoyl-CoA desaturase (SCD) which is the rate-limiting enzyme in the cellular synthesis of monounsaturated fatty acids from saturated fatty acids. A proper ratio of saturated to monounsaturated fatty acids contributes to membrane fluidity. Alterat...

Obesity is defined as an accumulation of excessive amounts of adipose tissue in the body, and predisposes to a variety of diseases including diabetes mellitus, and osteoarthritis. In most animals, obesity is the result of a simple imbalance between energy intake and energy expenditure. Therefore, at its simplest, successful management of obesity usually involves reversing this imbalance by redu...

Western Ontario, London, Ontario, Canada. Received for publication October 28, 1964; revised May 21, 1965. fluence of hormonal stimulation and Nandi (42) empha sized the importance of the milk agent in inducing hy PerPlastic alveolar nodules and eventual tumor. 1\Iice without the milk agent may be infected by ingestion or injection of milk, by injection of semen (5, 38), or by transplantation o...

Western Ontario, London, Ontario, Canada. Received for publication October 28, 1964; revised May 21, 1965. fluence of hormonal stimulation and Nandi (42) empha sized the importance of the milk agent in inducing hy PerPlastic alveolar nodules and eventual tumor. 1\Iice without the milk agent may be infected by ingestion or injection of milk, by injection of semen (5, 38), or by transplantation o...

BACKGROUND Obesity is a strong predictor of fecundity and maternal obesity may well program semen quality during pregnancy, but to our knowledge, no published studies have evaluated this hypothesis. METHODS From a Danish pregnancy cohort established in 1984-87, 347 out of 5109 sons were selected for a follow-up study conducted from February 2005 to January 2006. Semen and blood samples were a...

Prediction of seminal quality with statistical learning tools is an emerging methodology in decision support systems in biomedical engineering and is very useful in early diagnosis of seminal patients and selection of semen donors candidates. However, as is common in medical diagnosis, seminal quality prediction faces the class imbalance problem. In this paper, we propose a novel supervised ens...

PURPOSE We aimed to compare the associations between semen quality, associated reproductive indicators and the main prostate-related parameters in middle-aged men. MATERIALS AND METHODS This is a prospective study on 422 middle-aged men who underwent the screening for prostate health. Their reproductive function, semen quality and prostate-related pathologies were investigated. RESULTS Sign...

BACKGROUND Besides the well-known adverse effects of valproate (VPA), disorders related to male reproductive functions have been reported. Furthermore, only a limited number of previous studies have reported the relationship between VPA dose and impairment of the hormonal axis and semen quality. A patient with reversible changes that occurred in the sperm parameters after a dose increment of VP...

Background: Polycystic ovary syndrome (PCOS) is a well-known gynecological hormonal imbalance. The consequences of PCOS pose substantial risk for the development metabolic and cardiovascular abnormalities similar to those that make up (MBS). Therefore, there was need identify predictors MBS in subjects study their strength association.Methods: A prospective observational carried on 100 having f...