The human auditory system is divided into three main parts: outer, middle and inner auditory system. The auditory system is mainly responsible for hearing and balance. The Cochlea, which is present in the inner auditory system, consists of Basilar Membrane, Organ of Corti, OHC and IHC together execute the hearing mechanism. Otoacoustic Emissions are inaudible sounds which come out from the inne...

Distortion-product otoacoustic emissions (DPOAEs) were weak or absent in about one-third of sheep (Ovis aries) of both sexes tested for otoacoustic emissions (OAEs) even though their click-evoked OAEs (CEOAEs) seemingly were typical of other sheep of the same sex. Various pieces of evidence suggest that the absence of measurable DPOAEs was unlikely to be attributable to anesthetic effects, a po...

The most frequent hereditary hearing loss is caused by mutations in the GJB2 gene coding for the gap junction beta 2 protein Connexin 26 (Cx26). In contrast to many studies performed in patients with bi-allelic mutations, audiometric studies on heterozygotes are sparse and often contradictory. To evaluate hearing function in heterozygous carriers of the GJB2 c.35delG mutation, audiometry over t...

The aim of this study was to investigate the possible association between otoacoustic emission (OAE) values and cochlear function in patients with vitamin B12 deficiency and no evidence of symptomatic hearing loss. Two groups were studied: Group 1: patients with vitamin B12 deficiency; Group 2: a matched control group of patients with normal vitamin B12 levels. There was no evidence of symptoma...

Although several studies have documented the existence of sex differences in spontaneous otoacoustic emissions (SOAEs) and transient-evoked OAEs (TEOAEs) in humans, less has been published about sex differences in distortion-product OAEs (DPOAEs). Estimates of sex and ear differences were extracted from a data set of OAE measurements previously collected for other purposes. In accord with past ...

This critical review evaluated eight studies examining otoacoustic emissions (OAEs) in normal hearing individuals with Type I diabetes mellitus (DM) to determine if they are effective for characterizing subclinical auditory impairment as a result of the disease. All were prospective, non-randomized clinical cohort studies. Results indicate that despite normal hearing thresholds, otoacoustic emi...

Abstract Background Rheumatoid arthritis (RA) is an inflammatory autoimmune disorder that has cardinal articular and peri-articular symptoms. Extra-articular manifestations (EAMs) are also reported among RA patients. In the current study, we assessed hearing function in 50 An extensive audiological assessment including pure tone audiometry (PTA), extended high-frequency (EHFA), tympanometry, ac...

The Variational Autoencoder (VAE) suffers from a significant loss of information when trained on non-stationary data distribution. This in VAE models, called catastrophic forgetting, has not been studied theoretically before. We analyse the forgetting behaviour continual generative modelling by developing new lower bound likelihood, which interprets process as an increase probability distance b...

Time-domain simulations of the response to click of a human ear show that, if the cochlear amplifier gain (CAG) is a smooth function of basilar-membrane (BM) position, the filtering performed by a middle ear with an irregular (non-smooth) transfer function suffices to produce irregular and long-lasting residual BM oscillations at selected frequencies. Feeding back to the middle ear through hydr...