نتایج جستجو برای: nucleolus
تعداد نتایج: 3325 فیلتر نتایج به سال:
The nucleolus is the site of rRNA gene transcription, rRNA processing, and ribosome biogenesis. However, the nucleolus also plays additional roles in the cell. We isolated nucleoli using fluorescence-activated cell sorting (FACS) and identified nucleolus-associated chromatin domains (NADs) by deep sequencing, comparing wild-type plants and null mutants for the nucleolar protein NUCLEOLIN 1 (NUC...
When cells are observed by phase contrast microscopy, nucleoli are among the most conspicuous structures. The nucleolus was formally described between 1835 and 1839, but it was another century before it was discovered to be associated with a specific chromosomal locus, thus defining it as a cytogenetic entity. Nucleoli were first isolated in the 1950s, from starfish oocytes. Then, in the early ...
Are they always about? Not necessarily. They come and go, disappearing in mitosis from late prophase until telophase. During this period, some nucleolar antigens, including RNA polymerase I and topoisomerase I, remain associated with tandemly repeated clusters of ribosomal RNA genes on the condensed chromatin — these chromosomal regions are presumptuously known as nucleolar organising regions (...
The role of the nucleolus in the transfer of RNA from nucleus to cytoplasm was examined by means of experiments in which the nucleolus or other parts of the nucleus were inactivated by a microbeam of ultraviolet light. These experiments confirmed previous work in showing that such inactivation of the nucleolus inhibited the appearance in the cytoplasm, not only of ribosomal RNA, but also of oth...
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