High image contrast in magnetic resonance imaging (MRI) can be achieved by hyperpolarizing the nuclei of interest. Dynamic nuclear polarization (DNP) is a method to create hyperpolarization where excited electron spins induce a larger nuclear spin polarization. Imaging material that has been hyperpolarized by DNP is also known as Overhauser-enhanced magnetic resonance imaging (OMRI). An imager ...

Thirty three compounds were obtained from the bulbs of Urginea maritima (Liliaceae). The compounds were identified by means of fast atom bombardment mass spectrometry (FAB-MS), nuclear magnetic resonance (1H-NMR), (13C-NMR), nuclear overhauser effects (NOE) and two dimensional (2D) NMR. Ten of them were new natural compounds. Nine were bufadienolides and only one was lignan in these compounds.

Nuclear magnetic resonance spectroscopy provides non-invasive and non-destructive access to the chemistry of human tissue in situ. Two studies presented in this issue of the Journal [1, 2] apply this new technique on skeletal muscle metabolism in patients with chronic lung disease. In the 1940s, E. Purcell and F. Bloch discovered that electromagnetic radio-frequency energy could be used to inte...

In the article there is described a frequency-sweep nuclear magnetic resonance (NMR) spectrometer when a static magnetic field runs at a fixed value. The repetitive frequency-sweep of oscillator is realized by a variable frequency divider in the feedback loop of the second-order Phase Locked Loop. The largest advantage of this system for the CW NMR spectrometer is a good possibility of repetiti...

Nuclear magnetic resonance (NMR) microscopy allows us to image and quantify the distribution of NMR-active nuclei in living specimens. Using high-field NMR microscopy at a magnetic field strength of 14.1 T and strong gradients up to 3 T m(-1), we show that separation of fat and water nuclear resonances in living insects can be achieved. In contrast to destructive conventional photometric and ma...

Nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI) are supremely important techniques with numerous applications in almost all branches of science. However, until recently, NMR methodology was limited by the time constant T1 for the decay of nuclear spin magnetization through contact with the thermal molecular environment. Long-lived states, which are correlated quantum state...

Nuclear magnetic resonance (NMR) spectroscopy and magnetic resonance imaging (MRI) provide non-invasive information about multiple nuclear species in bulk matter, with wide-ranging applications from basic physics and chemistry to biomedical imaging. However, the spatial resolution of conventional NMR and MRI is limited to several micrometres even at large magnetic fields (>1 T), which is inadeq...

In this paper, an automatic determination algorithm for nuclear magnetic resonance (NMR) spectra of the metabolites in the living body by magnetic resonance spectroscopy (MRS) without human intervention or complicated calculations is presented. In such method, the problem of NMR spectrum determination is transformed into the determination of the parameters of a mathematical model of the NMR sig...