نتایج جستجو برای: ns3 and bvdv

تعداد نتایج: 16827762  

Journal: :hepatitis monthly 0
maryam dadmanesh department of infectious diseases, school of medicine, aja university of medical sciences, tehran, ir iran mohammad mehdi ranjbar department of immunology, school of medicine, aja university of medical sciences, tehran, ir iran seyed moayed alavian baqiyatallah research center for gastroenterology and liver diseases, baqiyatallah university of medical sciences, tehran, ir iran; middle east liver diseases research center (meld), tehran, ir iran; iran hepatitis network, tehran, ir iran khodayar ghorban department of immunology, school of medicine, aja university of medical sciences, tehran, ir iran; corresponding author: khodayar ghorban, department of immunology, school of medicine, aja university of medical sciences, tehran, ir iran. tel: +98-9127138775, e-mail:

conclusions overall, results of present study were consistent with the data reported earlier base on 5’ ntr in iranian isolates and revealed genotype ir2 is major genotype in iranian hgv-positive patient. it means there are higher similarities between iranian and europe-usa in hgv ns3 gene. results nucleotide blast results emphasized that most similar sequences to ir ns3 sequences were those fr...

ژورنال: :hepatitis monthly 0
zahra khanlari department of medical virology, faculty of medical sciences, tarbiat modares university, tehran, ir iran farzaneh sabahi department of medical virology, faculty of medical sciences, tarbiat modares university, tehran, ir iran; corresponding author: farzaneh sabahi, department of medical virology, faculty of medical sciences, tarbiat modares university, tehran, ir iran. tel: +98-2182883880, fax: +98-2182884555, e-mail: seyed younes hosseini gastroenterohepatology research center, shiraz university of medical sciences, shiraz, ir iran mostafa ghaderi department of medical virology, faculty of medical sciences, tarbiat modares university, tehran, ir iran

background hepatitis c virus (hcv) is able to down-regulate innate immune response. it is important to know the immune pathways that this virus interacts with. hcv non-structural protein 3 (ns3) plays an important role in this viral feature. hcv ns3 protein could affect the expression of antiviral protein such as viperin, and interleukin 28whichare important proteins in antiviral response. conc...

Background and Aims: Hepatitis C virus (HCV) infection is an important risk factor for the development of liver cancer. The HCV NS3 protein plays a key role in the virus life cycle and can affect normal cellular activities, such as cell proliferation, cell death, and cell signaling pathways. Moreover, it may influence malignancy development. Two cellular genes, heat shock protein 70 (HSP70) and...

Journal: :Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc 2011
Julia F Ridpath Gayla Lovell John D Neill Thomas B Hairgrove Binu Velayudhan Richard Mock

Although the causative agent of bovine viral diarrhea was initially categorized as 1 species, phylogenetic analysis revealed that these viruses belong to 2 different species, Bovine viral diarrhea virus 1 (BVDV-1) and BVDV-2, with 2-11 subgenotypes within each species. Distribution of species and subgenotypes has been shown to vary with geographic region. Whether distribution shifts over time i...

A. Khodakaram-Tafti, A. Mohammadi, GH. Farjani Kish

Bovine viral diarrhea virus (BVDV) is one of the most important viral pathogens of cattle worldwide. The aim of present study was to determine the molecular characterization and phylogenetic analysis of BVDV infection in dairy herds of Fars province, Iran. For initial screening, a total of 400 blood samples were collected from 12 industrial dairy herds with previous history of diarrhea, abortio...

2007
Dong-Kun Yang Byoung-Han Kim Chang-Hee Kweon Jeong-Kyu Park Ha-Young Kim Byung-Jae So In-Joong Kim

To characterize the genetic diversity of bovine viral diarrhea viruses (BVDV) circulating in Korea, 11 BVDV isolates were obtained from 467 field samples collected during 2005~2006 in Korea. All of the BVDV isolates were identified as non-cytopathic (non-cp) BVDV biotypes. The 5' noncoding region (NCR) genes of the isolates were sequenced and analyzed. In total, ten BVDV isolates were typed as ...

2016
Li Mao Wenliang Li Leilei Yang Jianhui Wang Suping Cheng Yong Wei Qiusheng Wang Wenwen Zhang Fei Hao Yonglong Ding Yinhua Sun Jieyuan Jiang

BACKGROUND Bovine viral diarrhea virus (BVDV) is a pathogen of domestic and wildlife animals worldwide and is associated with several diseases. In China, there are many reports about genotyping of BVDV strains originated from cattle and pigs, and some of them focused on the geographical distributions of BVDV. Currently, the goat industry in Jiangsu province of China is under going a rapid expan...

BIV is a well-known bovine immunosup-pressive cause, but its pathogenesis has not been well characterized. It seems that it is possible that cofactors such as co- infection with other bovine viral pathogens may play a role in enhancing the pathogenesis of BIV infection; BVDV also has immunosuppressive effects. OBJECTIVE: The aim of this study was determination of possible correlation between BI...

Journal: :Viral immunology 2004
Janice J Endsley Julia F Ridpath John D Neill Matthew R Sandbulte James A Roth

Passive antibody to bovine viral diarrhea virus (BVDV) acquired through colostrum intake may interfere with the development of a protective immune response by calves to this virus. The objective of this study was to determine if calves, with a high level of maternal antibody to bovine viral diarrhea virus (BVDV), develop CD4(+), CD8(+), or gammadelta T lymphocyte responses to BVDV in the absenc...

Journal: :Vaccine 2010
Wenzhi Xue Debra Mattick Linda Smith Jerry Umbaugh Emilio Trigo

Vaccination plays a significant role in the control of bovine viral diarrhea virus (BVDV) infection and spread. Recent studies revealed that type 1b is the predominant BVDV type 1 subgenotype, representing more than 75% of field isolates of BVDV-1. However, nearly all current, commercially available BVDV type 1 vaccines contain BVDV-1a strains. Previous studies have indicated that anti-BVDV ser...

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