Radiotherapy is a standard treatment for cancer and is used since a long time as a stand-alone therapy or in combination with surgery and systemic therapies including immunotherapy. Its acts through induction of irreversible DNA damage to which tumor cells are more susceptible because of frequent mutations in DNA repair pathways. Fractioned radiotherapy, given as daily low doses during multiple...

Nature recreation conflicts with conservation, but its impacts on wildlife are not fully understood. Where recreation is not regulated, visitors to natural areas may gather in large numbers on weekends and holidays. This may increase variance in fitness in wild populations, if individuals whose critical life cycle stages coincide with periods of high human disturbance are at a disadvantage. We ...

Background. The seasonality of influenza is thought to vary according to environmental factors and human behavior. During winter holidays, potential disease-causing contact and travel deviate from typical patterns. We aim to understand these changes on age-specific and spatial influenza transmission. Methods. We characterized the changes to transmission and epidemic trajectories among children ...

BRIDGE # # Bridge = 1 week introduction to the clinical blocks. (Dotted lines denote 4 week segments within a block) Other than the two week vacation period over the Christmas and New Years Holidays vacation period each year, students are expected to assume the professional responsibilities of the service on which they are rotating. There will be no set days off for Memorial Day, July 4, Labor ...