In this paper, we introduce the concepts of average and projected systems associated to a coherent (parent) system. We analyze several aspects of these notions and show that they can be useful tools in studying the performance of coherent systems with nonexchangeable components.We show that the average and projected systems are especially useful in studying the tail behavior of reliability, haz...

A method is given for preparing tubulin with 1 mol of exchangeably bound [gamma-32P]GTP/mol of 6 S dimer. Bovine tubulin is shown to hydrolyze 1 mol of GTP/mol of 6 S dimer added to assembling microtubules at 37 degrees. Hydrolysis and assembly occur at the same rate and to the same extent. When microtubule-associated proteins (MAPs) are removed, both hydrolysis and assembly fail to occur. Read...

The nonexchangeable base and sugar protons of the octanucleotide d(G-G-A-A-T-T-C-C) have been assigned by two-dimensional correlated (COSY) and nuclear Overhauser effect (NOESY) methods in aqueous solution. The assignments are based on distance connectivities of 4 . 5 A established from NOE effects between base and sugar protons on the same strand and occasionally between strands, aswell as,...

Conventional approaches to statistical inference preclude structures that facilitate incorporation of supplemental information acquired from similar circumstances. For example, the analysis of data obtained using perfusion computed tomography to characterize functional imaging biomarkers in cancerous regions of the liver can benefit from partially informative data collected concurrently in non-...

Microtubules are highly dynamic and switch stochastically between growing and shrinking phases both in vivo and in vitro. This non-equilibrium behavior, known as dynamic instability, is based on the binding and hydrolysis of GTP at the nucleotide exchangeable site (E-site) in β-tubulin. Only dimers that have GTP in their E-site can polymerize (red tubulin subunits), but following polymerization...

We consider the problem of explicitly pricing and hedging an option written on a nonexchangeable asset when trading in a correlated asset is possible. This is a typical case of incomplete market where it is well known that the super-replication concept provides generally too high prices. Here, following J.H. Cochrane and J. Saá-Requejo, we study valuation under No Good Deal (NGD) Assumption. Fi...

Several methods have recently been developed for joint structure learning of multiple (related) graphical models or networks. These methods treat individual networks as exchangeable, such that each pair of networks are equally encouraged to have similar structures. However, in many practical applications, exchangeability in this sense may not hold, as some pairs of networks may be more closely ...

Hybrid networks, including physical and chemical cross-links, were synthesized from biosourced fatty acid fragments, linked to each other by a controlled number of nonexchangeable ether bonds, exchangeable ester noncovalent hydrogen bonds. The mechanical properties these networks are tuned the ratio di- versus tetraepoxide stoichiometry acid/epoxy. Creep tests insolubility demonstrated vitrimer...