نتایج جستجو برای: non small cell lung cancer
تعداد نتایج: 4065786 فیلتر نتایج به سال:
Background: Lung cancer is the most common cause of cancer death worldwide with an annual mortality rate of more than 1.3 million worldwide. We aimed to analyze the clinicopathological features of patients with non-small-cell lung cancer (NSCLC) in west of Iran. Methods: 64 patients with NSCLC who referred to our clinic were analyzed. Sex, age, histopathology, location of the tumor, treatment,...
Background: Tumor radioresistance leads to a reduction in the efficiency of radiation therapy. It is very important to explore the cellular mechanisms leading to radioresistance and to find potential therapeutic targets, which might improve the efficacy of radiation therapy. This study was to investigate the role of ataxia-telangiectasia mutated (ATM) and murine double minute X (MDMX) in radior...
H Endon et al (JCO 2004;22:811-9). Selected 8 genes out of 44 detected as prognostic markers of adenocarcinoma (Garber et al PNAS USA 98;13784-9, 2001 and Bhattachorjee et al PNAS USA 98;13790-5, 2001): PTK 7 (HR 0.5), CIT (HR 0.6), SCNNIA (HR 1.7), PGES (HR 2.2), EST-LB4D (HR 1.9), ERO 1l (HR 0.2), EST-AA434256 (HR 0.4) and ZWINT (HR 2.3). Low risk group had a 85% 5 y OS and high risk 40% 5 y OS.
Downloa development of molecular markers is crucial for improving therapy in advanced non-small cell ancer (NSCLC). Here, we review perspectives of biomarker-driven personalized therapy in NSCLC, articular reference to the detection of EML4-ALK gene rearrangements. Different molecular assays, with p validation, and clinical application to different types of tissue specimens are discussed. Clin ...
The objective was the drafting of a document describing the technique of tridimensional conformal irradiation of a non small cell lung cancer (NSCLC). Principles and recommendations concern patients affected by lung cancer localized in the thorax and inoperable or patients who must undergo postoperative irradiation. They have been developed according to the current scientific data from an analy...
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