Purpose: The PAP smear has significantly reduce the mortality and morbidity of cancer cervix however there is some debates of it as interobserver variability and high false negative and false-positive rates so parameters of cell proliferation have emergedas important diagnostic and prognostic tools. Aim of the Work: This present study aimedtoevaluate the efficiency of Ki67 in differentiating dy...

The Swedish Cervical Cytology Biobank (SCCB) is the first national initiative of a prospective repository for liquid-based gynecological cell samples (LBC) from women participating in organized cervical cancer screening programs. Development and implementation of a nationally standardized method for the handling and long-term storage of cervical cell samples has been a primary goal for the Swed...

The paper addresses the presentation of the medical information system and describes its application for quality assurance (QA) programs under the conditions of Georgia rules. 100 gynecological cytology cases were randomly selected. Digital images were obtained on all cases. All 100 cases (medical data and images) have been uploaded into the medical information system and labeled “QA”. Diagnosi...

EGFR and KRAS mutations are two of the most common mutations that are present in lung cancer. Screening and detecting these mutations are of issue these days, and many different methods and tissue samples are currently used to effectively detect these two mutations. In this study, we aimed to evaluate the testing for EGFR and KRAS mutations by pyrosequencing method, and compared the yield of cy...

Background In women, peritoneal cancer is commonly associated to epithelial ovarian cancer. Ovarian carcinomatosis patient survival appears be better in comparison other Malignancies, e.g., colorectal neoplasms or mesotheliomas. Here, we aim analyze the value of CA125, CEA, CA125/CEA ratio (CCR) tumor markers as preoperative tools for diagnosis Material and methods: From 2005-2008, recruit pros...

Background: Abdominal cutaneous and subcutaneous nodules are uncommon benign or malignant lesions. The majority of the malignant nodules are metastatic in origin and may be the initial presentation of a primary malignancy; hence, an early diagnosis is important. Our aim of this study was to find out the spectrum of lesions (both non-neoplastic and neoplastic) that present as cutaneous and subcu...

BACKGROUND Although human immunodeficiency virus (HIV)-infected women are at high risk for anal cancer, few data have been published on prevalence of and risk factors for anal precancer and potential screening strategies in this risk group. METHODS A cross-sectional anal screening study was nested in a gynecological cohort of HIV-infected women. Anal swab specimens were collected for cytology...