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â  â  no treatment has been proven to be effective in nonalcoholic fatty liver disease (nafld) and/or steatohepatitis (nash). numerous studies have addressed this issue. however conclusive recommenâ­dations cannot be drawn solely from the currently available studies. hence we performed this systematic review to determine which of the available therapeutic modalities are supported by adequate ev...

background: nonalcoholic fatty liver disease (nafld) is becoming a significant problem especially through substantial increase in the incidence of obesity worldwide. currently it is the most common cause of abnormal serum aminotransferase levels both in low- and middle-income countries and in high-income countries and despite its high prevalence, well-defined screening recommendations are curre...

conclusions the results confirmed that the total costs for non-alcoholic fatty liver among the iranian adult urban population alone exceeded 1 billion ppp$ per year. these costs can be saved or reduced by effective disease management and early prevention. objectives this study aims to estimate the diagnosis and treatment costs of non-alcoholic fatty liver. patients and methods this cross-sectio...

introduction worldwide, chronic liver disease is a major cause of morbidity and mortality. causes of elevated serum alanine aminotransferase (alt) levels vary depending on the population under study. the aim of this study is to evaluate the frequency and causes of persistently elevated alt levels in patients of the gastroenterology (gi) clinics in ghaem and emam reza hospitals in mashhad, iran....

background :timely diagnosis of liver cirrhosis is vital for preventing further liver damage and giving the patient the chance of transplantation. although biopsy of the liver is the gold standard for cirrhosis assessment, it has some risks and limitations and this has led to the development of new noninvasive methods to determine the stage and prognosis of the patients. we aimed to design an a...

conclusion the prevalence of nafld in this group of iranian adult general population is 21.5%. nafld in iranian population is associated with male gender, old age, obesity, and features of metabolic syndrome. results 819 subjects were included in this study among which were 340 males (41.5%) and 479 females (58.5%) with the mean age of 43.1 ± 14.1 years. nafld was diagnosed in 176 (21.5%) subje...

conclusions lepr q223r polymorphisms may confer a significant risk of nafld and coronary atherosclerosis. the a allele in the k109r polymorphism might be considered an independent risk factor for coronary atherosclerosis in nafld patients. objectives to investigate the association of lepr polymorphisms at q223r and k109r with the risks of nafld and coronary atherosclerosis in the chinese han po...

results although a hypocaloric diet could prevent the progression of fat accumulation in liver, the diet composition is another aspect which should be considered in diet therapy of patients with nafld. conclusions several studies assessed the effects of dietary composition on fat storage in liver; however, their findings are inconsistent. most studies focused on the quantity of carbohydrate and...