نتایج جستجو برای: nitroimidazole

تعداد نتایج: 662  

Journal: :international journal of advanced biological and biomedical research 2014
seyede saeedeh mosallanejad hadi tavakkoli amin derakhshanfar sajedeh salandari

nitroimidazole compounds have been traditionally used in the veterinary and human medicine, but their uses are sometimes associated with some side effects. toxicopathological effects of nitroimidazoles have always been a major concern. there is scant information available about the pathological alterations of nitroimidazole compounds in the embryo. the objective of this study was to determine t...

Journal: :The journal of physical chemistry. A 2013
Zijun Yu Elliot R Bernstein

New imidazole-based energetic molecules (1,4-dinitroimidazole, 2,4-dinitroimidazole, 1-methyl-2,4-dinitroimidazole, and 1-methyl-2,4,5-trinitroimidazole) are studied both experimentally and theoretically. The NO molecule is observed as a main decomposition product from the above nitroimidazole energetic molecules excited at three UV wavelengths (226, 236, and 248 nm). Resolved rotational spectr...

Journal: :International journal of epidemiology 2002
Lori A Fischbach Karen J Goodman Mark Feldman Corinne Aragaki

BACKGROUND A vast number of Helicobacter pylori treatment trials have been conducted. Regimens may vary in efficacy in different patient populations. METHODS We identified sources of treatment effect variation from 618 treatment groups using weighted cross-classified multi-level meta-regression models. Summary effect estimates were calculated within groups that lacked identified heterogeneity...

Journal: :The Journal of antimicrobial chemotherapy 2000
M Castelli M Malagoli L Lupo S Roffia F Paolucci C Cermelli A Zanca G Baggio

Sulphimidazole (1-methyl-2((4-aminophenyl)-sulphonyl)-amino-5-nitroimidazole) is a new compound in which a p-aminobenzenesulphonamide radical has been attached at position 2 of the 5-nitroimidazole ring. It possesses a useful spectrum of activity in vitro against various anaerobic microorganisms and its action against aerobic and facultative bacteria is synergically enhanced in association with...

Journal: :Anticancer research 2005
Werner Krause Andreas Jordan Regina Scholz José-Luis Martin Jimenez

Four different nitroimidazole derivatives, with up to two iodine atoms on the imidazole ring, were investigated for their radiosensitizing potency under hypoxic conditions, in order to test whether the introduction of iodine atoms increases the radiosensitizing potency of nitroimidazoles. Misonidazole and metronidazole were used as controls. Human colonic adenocarcinoma cells were incubated wit...

2009
Alka MITAL

Parasitic and bacterial infections affecting the gastrointestinal tract represent a significant cause of morbidity and mortality worldwide. Nitroheterocyclic drugs have been available since the early 1960s for the treatment of anaerobic protozoa. The application of these drugs has widened and they are presently used to treat anaerobic pathogenic bacteria and protozoa. 5-nitroimidazoles are a we...

Journal: :Journal of clinical microbiology 2004
Jeffrey M Schapiro Rachna Gupta Eric Stefansson Ferric C Fang Ajit P Limaye

Members of the Bacteroides fragilis group are among the most common anaerobic bacterial isolates in clinical specimens. Metronidazole, a 5-nitroimidazole, is often used as empirical therapy for anaerobic infections. Susceptibility testing is not routinely performed because of nearly universal susceptibility of Bacteroides spp. to this agent. We report a case of metronidazole-resistant Bacteroid...

Journal: :Physical Chemistry Chemical Physics 2015

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