On admixture of non-ionic surfactant of the alkyl or dialkyl polyglycerol ether class and cholesterol with subsequent hydration in aqueous media, microscopic lamellar structures formed are known as niosomes or non-ionic surfactant vesicles. Method of preparation of niosome is same as of liposome technology i.e. hydration by aqueous phase of the lipid phase which may be either a pure surfactant ...

Objective(s): The purpose of the present study was to prepare and to evaluate a novel niosome as transdermal drug delivery system for propranolol hydrochloride and to compare the in vitro efficiency of niosome by either thin film hydration or hand shaking method. Materials and Methods: Niosomes were prepared by Thin Film Hydration (TFH) or Hand Shaking (HS) method. Propranolol niosomes were pre...

Background: Due to the increase in cancer and side effects of common therapies, researchers are looking for treatments with the least side effects, which is why medicinal plants have become so important. Adiantum capillus-veneris L. plant commonly called southern maidenhair fern, and also named as “Pare-siavashan” in medical and pharmaceutical textbooks of Iranian Traditional Medicine, contains...

The plasma pharmacokinetic study of abacavir sulphate was investigated after oral administration free solution, freshly prepared niosomal and proniosomal dispersions. loaded niosome vesicles were by the thin-film hydration method proniosomes slurry using tween 60 as surfactant cholesterol a membrane stabilizer dicetyl phosphate negative charge inducer. Maltodextrin used carrier in proniosome fo...

Drug delivery systems comprising vesicles prepared from one amphiphile encapsulating vesicles prepared from a second amphiphile have not been prepared previously due to a tendency of the bilayer components of the different vesicles to mix during preparation. Recently we have developed polymeric vesicles using the new polymer-palmitoyl glycol chitosan and cholesterol in a 2:1 weight ratio. These...