نتایج جستجو برای: nimorazole
تعداد نتایج: 46 فیلتر نتایج به سال:
As the molecular mechanisms behind tumor hypoxia have now been delineated, the important conclusion of the radiation oncologist Dr. Okuyama that “hypoxic milieu as the primary cancer environment” needs to be reexamined for its impact on current cancer diagnosis and treatment. It is apparent that, although hypoxic tumor cells cannot live without oxygen and nutrients, aggressive tumor cells isola...
Till date, most of the drugs have been given in conventional immediate release dosage form. Nimorazole is an anticancer drug, used as a hypoxic radiosensitizer in patients undergoing radiotherapy and no formulation has been available in the market till now. Hence, for the purpose to develop an immediate release dosage form, a statistical optimization process has been employed to quantify the ef...
BACKGROUND Although head and neck cancer can be cured by radiotherapy, the optimum treatment time for locoregional control is unclear. We aimed to find out whether shortening of treatment time by use of six instead of five radiotherapy fractions per week improves the tumour response in squamous-cell carcinoma. METHODS We did a multicentre, controlled, randomised trial. Between January, 1992, ...
UNLABELLED A systematic review of radiation therapy trials in several tumour types was performed by The Swedish Council of Technology Assessment in Health Care (SBU). The procedures for evaluation of the scientific literature are described separately (Acta Oncol 2003; 42: 357-365). This synthesis of the literature on radiation therapy for head and neck cancer is based on data from 39 randomized...
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