Nek6 and Nek7 are evolutionarily conserved murine kinases structurally related to the Aspergillus mitotic-regulator NIMA (Genomics 68 (2000) 187). Comparative in situ examination of their patterns of expression revealed that during early embryogenesis nek6 is highly expressed in primary giant trophoblast cells, while nek7 is expressed in the site of decidual reaction. Later in embryogenesis, bo...

Non-inherited maternal antigens encoded by specific HLA-DRB1 alleles (NIMA) have been implicated as a rheumatoid arthritis (RA) risk factor. Using genotype data from North American Rheumatoid Arthritis Consortium study participants and the maternal-fetal genotype incompatibility (MFG) test, we find evidence for offspring allelic effects but no evidence for NIMA as a RA risk factor. We discuss p...

TBD Nima Arkani-Hamed (IAS): Thoughts on Particle Dark Matter

LINK TO PAPER Evaluation of an Assisted Feature Extraction System Track: Remote Sensing Imagery Author(s): Michael A. O'Brien The extraction of geospatial information from imagery is generally a labor-intensive process. Automated tools that could assist analysts in this process would be of tremendous benefit for production at the National Imagery and Mapping Agency (NIMA). This paper examines a...

In haploidentical transplantation, the mismatched haplotype of the donor can originate from either of the parents. We refer to such mismatched haplotypes as noninherited maternal antigens (NIMA haplotype) or noninherited paternal antigens (NIPA haplotype). To determine whether exposure to maternal HLA antigens benefits patients undergoing bone marrow transplantation, we analyzed graft failure a...

We have cloned Pfnek-1, a gene encoding a novel protein kinase from the human malaria parasite Plasmodium falciparum. This enzyme displays maximal homology to the never-in-mitosis/Aspergillus (NIMA)/NIMA-like kinase (Nek) family of protein kinases, whose members are involved in eukaryotic cell division processes. Similar to other P. falciparum protein kinases and many enzymes of the NIMA/Nek fa...

Automatically learned quality assessment for images has recently become a hot topic due to its usefulness in a wide variety of applications such as evaluating image capture pipelines, storage techniques and sharing media. Despite the subjective nature of this problem, most existing methods only predict the mean opinion score provided by datasets such as AVA [1] and TID2013 [2]. Our approach dif...

I n the article by Eapen et al, “Soluble Urokinase Plasminogen Activator Receptor Level Is an Independent Predictor of the Presence and Severity of Coronary Artery Disease and of Future Adverse Events,” which published online October 23, 2014, and appeared in the October 2014 issue of the journal (J Am Heart Assoc. 2014;3:e001118 doi: 10.1161/ JAHA.114.001118), one of the authors’ names appeare...

Exposure to non-inherited maternal antigens (NIMA) has life-long immunological consequences that may result in tolerance or immunity to these antigens. Gaining understanding of the mechanisms behind these NIMA effects will impact many areas of immunology. This review summarizes new discoveries relevant to autoimmunity and organ transplantation regarding exposure to maternal antigens. In light o...

Mark Here Section Time Location GSI 1 9-10am 6 Evans Ramtin 2 10-11am 71 Evans Ramtin 3 11-12pm 71 Evans Nima 4 12-1pm 2 Evans Nima 5 1-2pm 87 Evans Sridhar 6 2-3pm 2070 VLSB Sridhar 7 3-4pm 85 Evans Chung-Wei 8 4-5pm 9 Evans Chung-Wei 9 5-6pm 9 Evans Richard 10 1-2pm 3105 Etch. Chenyu 11 2-3pm 151 Barr. Kate 12 4-5pm B51 Hilde. Richard 13 6-7pm 70 Evans Sibi 14 12-1pm 101 Wheel. Chenyu 15 4-5p...