Idiopathic retinal vasculitis, aneurysms, and neuroretinitis (IRVAN) syndrome typically affects young, healthy individuals. Despite the dramatic fundus appearance seen in this syndrome, these patients are usually asymptomatic. The syndrome includes peculiar vascular abnormalities in the form of multiple aneurysmal dilatations seen along retinal arterioles and optic nerve-head arterioles, which ...

IRVAN syndrome is a rare disease characterized by retinal vasculitis, retinal aneurysms and neuroretinitis. Patients are usually asymptomatic at diagnosis but over time, proliferative changes, macular hard exudates, macular edema and retinal vascular occlusions can lead to severe vision loss. In this article we review the signs, symptoms, workup and treatment options of this disease.

We report a case series of neuroretinitis in ocular bartonellosis and describe the serologic verification for Bartonella henselae. This is a retrospective interventional case series of four patients who presented in the ophthalmology clinic of Hospital Universiti Sains Malaysia from June 2012 to March 2013. All four patients had a history of contact with cats and had fever prior to ocular sympt...

PURPOSE To describe an unusual case of idiopathic retinal vasculitis, aneurysms, and neuroretinitis syndrome associated with a positive perinuclear antineutrophil cytoplasmic antibody test. METHODS This is an interventional case report. A 22-year-old man with decreased vision underwent ophthalmoscopic, angiographic, and laboratory evaluation. The left eye underwent laser therapy due to circin...

PURPOSE To report the findings of optical coherence tomography (OCT) in three cases of diffuse unilateral subacute neuroretinitis (DUSN). METHODS Three young patients with confirmed diagnosis of diffuse unilateral subacute neuroretinitis were followed-up using Stratus OCT. RESULTS Optical coherence tomography findings included retinal nerve fiber layer atrophy and focal edema where the worm...