نتایج جستجو برای: neurooncology
تعداد نتایج: 163 فیلتر نتایج به سال:
A hypoxic microenvironment induces resistance to alkylating agents by activating targets in the mammalian target of rapamycin (mTOR) pathway. The molecular mechanisms involved in this mTOR-mediated hypoxia-induced chemoresistance, however, are unclear. Here we identify the mTOR target N-myc downstream regulated gene 1 (NDRG1) as a key determinant of resistance toward alkylating chemotherapy, dr...
Deadline: March 23, 2014 Early Registration: June 15, 2014
Abstract PROBLEM Data quality impacts the validity of results obtained through clinical research due to several reasons. These include degradation tumor tissue and other biological samples while being transported across large distances. Other concerns related data collection breach in patient privacy loss corruption data. Such issues lead generation that are either unreliable or unsuitable for ...
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