نتایج جستجو برای: neuromedin s

تعداد نتایج: 711493  

Journal: :Endocrinology 2002
A M Wren C J Small C R Abbott P H Jethwa A R Kennedy K G Murphy S A Stanley A N Zollner M A Ghatei S R Bloom

The central nervous system and gut peptide neuromedin U (NMU) inhibits feeding after intracerebroventricular injection. This study explored the hypothalamic actions of NMU on feeding and the hypothalamo-pituitary-adrenal axis. Intraparaventricular nucleus (intra-PVN) NMU dose-dependently inhibited food intake, with a minimum effective dose of 0.1 nmol and a robust effect at 0.3 nmol. Feeding in...

Journal: :Neuron 2015
Ivan T. Lee Alexander S. Chang Manabu Manandhar Yongli Shan Junmei Fan Mariko Izumo Yuichi Ikeda Toshiyuki Motoike Shelley Dixon Jeffrey E. Seinfeld Joseph S. Takahashi Masashi Yanagisawa

Circadian behavior in mammals is orchestrated by neurons within the suprachiasmatic nucleus (SCN), yet the neuronal population necessary for the generation of timekeeping remains unknown. We show that a subset of SCN neurons expressing the neuropeptide neuromedin S (NMS) plays an essential role in the generation of daily rhythms in behavior. We demonstrate that lengthening period within Nms neu...

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