PURPOSE A key challenge for providers and commissioners of rehabilitation services is to find optimal balance between service costs and outcomes. This article presents a "real-life" application of the UK Rehabilitation Outcomes Collaborative (UKROC) dataset. We undertook a comparative cohort analysis of case-episode data (n = 173) from two specialist neurological rehabilitation units (A and B),...

infective endocarditis can complicate with ischemic stroke. neurological complications develop in 20-40% of all patients with infective endocarditis. these are mainly due to vegetation embolism.this report represents a case of 30 years old female patient who presented with features of heart failure new york heart association (nyha) class iv with infective endocarditis and left hemiparesis. on e...

the short and long term effects of chromium toxicity on brain catecholamines and acetylcholinesterase levels were investigated. rats were injected daily with varying amounts of chromium. the short term (2 h) administration of chromium (8 mmol/kg) reduced catecholamines level of cerebellum, mid-brain and brain-cortex by 22.8, 19.4 and 21.2% respectively. acetylcholinesterase activity was also re...

tuberculous meningitis (tbm) and acute bacterial meningitis (abm) cause substantial mortality and morbidity in both children and adults. identification of poor prognostic factors at patient's admission could prepare physicians for more aggressive monitoring of patients with meningitis. the objective of this study was to determine the predictive value of neurological features to differentiate ab...

many studies concerning persian history have been performed. persian physicians and scientists greatly contributed to medical sciences by their own observations, experimentations and skills through more than seven thousand years of persian history. in persian medieval medicine, different fields were described. among these fields, neurological disorders, especially headache and epilepsy were exp...

multiple sclerosis is an inflammatory disease of the central nervous system in which t cells experience a second phase of activation, which ultimately leads to axonal demyelination and neurological disability. the recent advances in stem cell therapies may serve as potential treatments for neurological disorders. there are broad types of stem cells such as neural, embryonic, mesenchymal and hem...

clinical neurology has been traditionally considered as an academic speciality in which the specialist regurgitates his/her knowledge of neurology without being able to do much for the patient. this attitude is no longer acceptable. surge of information and discoveries in neurosciences within the last two decades translated into therapeutic interventions which is literally life saving in some o...

The functions of the glymphatic system include clearance metabolic waste and modulation water transport in brain, it forms a brain-wide fluid network along with cerebrospinal (CSF) interstitial (ISF). pathway consists periarterial influx CSF, astrocyte-mediated interchange between ISF CSF supported by aquaporin-4 (AQP4) on endfeet astrocyte around periarterioles, perivenous efflux CSF. Finally,...