The purpose of this investigation was to examine the effects of autonomic neurohormones, cyclic nucleotides, and related agents on the immunologic discharge of lysosomal enzymes from, and phagocytosis by, purified human neutrophils. In order to discern the possible intracellular mechanisms by which certain neurohormones influence neutrophil function, the concentrations of cyclic AMP and cyclic ...

Our present understanding of the physiology of appetite is still incomplete. However, we are aware that there are various endogenous brain messenger substances (neuro-transmitters, neurohormones) that effect, among other things, mood, memory, relaxation, focus, and appetite. A better appreciation of the relationship of these brain messenger chemicals to their nutritional building blocks, partic...

The physiological characteristics of two cardioacceleratory peptides (CAPs) were analysed in the tobacco hawkmoth, Manduca sexta, to determine if either CAP functioned as a cardioregulatory neurohormone. In vivo heart recordings from pharate and newly emerged adults revealed a dramatic increase in heart rate associated with wing-spreading behaviour. Bioassay of whole blood taken from wing-sprea...

One problem in aquaculture is obtaining brood because many commercially important species are incapable of spontaneous maturation under artificial conditions. Commercial shrimp hatcheries commonly use eyestalk ablation to stimulate gonadal maturation in shrimps. Research has been conducted on the inhibition of reproductive maturation by hormones originating in the eyestalk glands and on other e...

Considered biologically as well as philosophically, man is a most singular product of the evolutionary process. He receives and transmits not one but two heredities, the biological and the cultural. Man’s biological heredity is very much like that of any other organism; it is transmitted solely from parents to their children, and to other direct descendants. Cultural heredity, or simply culture...

A holistic approach to understanding the mechanisms by which stress influences the pathogenesis of infectious disease has resulted in the development of the field of microbial endocrinology. This transdisciplinary field represents the intersection of microbiology with mammalian endocrinology and neurophysiology, and is based on the tenet that microorganisms have evolved systems for using neuroh...