purpose: to report an unusual case of orbitocranial meningioma presenting in a neonate. methods: case report results: a 1-day-old neonate was presented with severe proptosis of the left eye. ct scan and mri showed an extensive mass with involvement of left orbit and brain. discrete calcification could be seen on ct scan. the patient did not have any signs of neurofibromatosis and family history...

Manifestations of central von Recklinghausen 's neurofibromatosis are well known and may include bilateral acoustic neuromas in the absence of peripheral neurofibromatosis or associated gliomas, meningiomas, other cranial nerve neuromas, optic nerve gliomas, and ependymomas [1]. A few reports deal specifically with the cranial CT findings in central neurofibromatosis [2-4]. One series [3] inclu...

Neurofibromatosis has been known to involve blood vessels throughout the body. Pulmonary involvement with interstitial fibrosing alveolitis has been described but no case of pulmonary vascular involvement has been reported to date. A 51 year old patient with cutaneous neurofibromatosis is described who presented with severe pulmonary hypertension and radiographic, scintigraphic, and angiographi...

Neurofibromatosis is a devasting autosomal dominant disease which is extremely variable in its symptomatology, intensity, and progression. There have been numerous reports published about the physical aspects of neurofibromatosis, while psychological issues have been given little attention so far. The present article presents a review of the current knowledge concerning psychological aspects of...

OBJECTIVE The aim of this study was to investigate the presence of growth hormone receptor in plexiform neurofibromas of neurofibromatosis type 1 patients. INTRODUCTION The development of multiple neurofibromas is one of the major features of neurofibromatosis type 1. Since neurofibromas commonly grow during periods of hormonal change, especially during puberty and pregnancy, it has been sugg...

Neurofibromatosis type 1 is characterized by cutaneous neurofibromas and pigmented lesions of the skin called café au lait spots. Although neurofibromatosis type 1 represents a major risk factor for the development of malignancy, especially of nervous system tumors, malignant lymphoma rarely occurs in a patients with neurofibromatosis type 1. Recently, a 77-year-old woman with neurofibromatosis...

Plexiform neurofibromas occur in about 60% of neurofibromatosis type 1(NF-1) patients and can lead to severe morbidity by disfigurement or compression of vital structures. Moreover, these tumors can undergo malignant transformation. Both focal and localized bone abnormalities are part of the phenotypic expression of NF-1. We report a rare case of severe cranioorbital plexiform neurofibromatosis...

A simultaneous finding of pseudoangiomatous stromal hyperplasia (PASH) and stromal multinucleated giant cells (MGC) in mammary tissue was previously observed in patients with type-1 neurofibromatosis, indicating that it can represent a morphologic marker for this syndrome. Here, we present PASH with MGC occurring in the left breast of a 39-years-old woman who does not have neurofibromatosis. Th...

The aim of this study was to evaluate vitamin B12 levels in the patients diagnosed with neurofibromatosis type 1 (NF1) and compare them a healthy group. In study, files patients, who were admitted pediatric neurology outpatient clinic tertiary university hospital followed up after being during 15-month period, evaluated retrospectively (Study group). Demographic data, laboratory test results (c...