Previously, comparisons of multiple strategies in health technology assessment have been undertaken on the incremental cost-effectiveness plane using efficiency frontiers and cost-effectiveness acceptability curves. This article proposes shifting the comparison of multiple strategies to the cost-disutility plane. Evidence-based decision making requires comparison of all strategies against each ...

BACKGROUND As the management of patients treated with anticoagulants and antiplatelet drugs entails balancing coagulation levels, we evaluated the net clinical benefit of warfarin and aspirin on stroke in a large cohort of patients with atrial fibrillation (AF). METHODS A population-based cohort study of all patients at least 18 years of age with a first-ever diagnosis of chronic AF during th...

Cost-optimal planning (COP) uses action costs and asks for a minimum-cost plan. It is sometimes assumed that there is no harm in using actions with zero cost or rational cost. Classical complexity analysis does not contradict this assumption; planning is PSPACE-complete regardless of whether action costs are positive or non-negative, integer or rational. We thus apply parameterised complexity a...

background: in order to provide guidance on the efficient allocation of health resources when handling public health emergencies in the future, the study evaluated the h1n1 influenza prevention and control program in hubei province of china using cost-benefit analysis. methods: the costs measured the resources consumed and other expenses incurred in the prevention and control of h1n1. the assum...

RESEARCH QUESTIONS AND CONTRIBUTIONS ■ How is net benefit for above models correlated with user satisfaction? Does higher net benefit always yield a satisfied user. ● While query cost-benefit models are strongly correlated with user satisfaction, search cost-benefit models have weaker correlation. ■ How do the coefficients in above models vary for search sessions on mobile? At present, coeffici...

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As the baby boom generation begins to retire and fiscal pressures from entitlement programs become more acute, evidence of improving health and increasing life expectancy in these cohorts has led many to suggest taking advantage of improved work capacity among older adults by increasing age requirements for the Social Security and Medicare programs. Currently, however, more than half of workers...

Background—Known risk factors for bleeding during anticoagulant treatment are largely the same as those predicting thromboembolic events in patients with atrial fibrillation (AF). Our objective was to investigate how to maximize the likelihood of avoiding both stroke and bleeding. Methods and Results—All 182 678 subjects with atrial fibrillation in the Swedish Hospital Discharge Register were s...