نتایج جستجو برای: nerve injury
تعداد نتایج: 462116 فیلتر نتایج به سال:
Although the nerve auto graft still remains the clinical Gold standard in repairing nerve injury gaps, many advances have been achieved to guide regenerating axons across the lesion. Functional recovery after peripheral nerve lesion is depended upon accurate regeneration of axons to their original target tissues. To increase the prospects of axonal regeneration and functional recovery, research...
a b s t r a c tintroduction: peripheral nerve injury is a common disorder and leads to permanent neurological defects. schwann cells have been shown to have nerve repair after being transplanted in peripheral nerve injury. the aim of this study was to determine the beneficial effect of allograft schwann cells on electrophysiological outcome after transection of the sciatic nerve in rats.methods...
A B S T R A C TIntroduction: Peripheral nerve injury is a common disorder and leads to permanent neurological defects. Schwann cells have been shown to have nerve repair after being transplanted in peripheral nerve injury. The aim of this study was to determine the beneficial effect of allograft Schwann cells on electrophysiological outcome after transection of the sciatic nerve in rats.Methods...
Introduction: Peripheral nerve damage is a clinical problem that causes sensory and motor disabilities. Sesamol is an antioxidant that can be effective in repairing various organs. The aim of this study was to evaluate the effect of different doses of sesamol on inflammation and pain in the damaged rat sciatic nerve. Materials and Methods: In this study, 35 adult male Wistar rats were used. The...
background: p2x4 receptor (p2x4r), a purinoceptor expressed in activated spinal microglia, plays a key role in the pathogenesis of neuropathic pain. spinal nerve injury induces up-regulation of p2x4r on activated microglia in the spinal cord, and blockade of this receptor can reduce neuropathic pain. the present study was undertaken to determine whether paroxetine, an inhibitor of p2x4r, could ...
Background and purpose: Injury to peripheral nerve causes widespread cellular and molecular changes in injured neurons, however, the mechanisms involved remain unknown. One of these changes is increased production of free radicals that causes oxidative stress. Antioxidants participate in nerve repair through the scavenging effect of oxygen free radicals. In this research we studied gene express...
Objective(s): Schwann cells (SCs) have a wide range of applications as seed cells in the treatment of nerve injury during transplantation. However, there has been no report yet on kinds of proteomics changes that occur in Schwann cells before and after peripheral nerve injury.Materials and Methods: Activated Schwann cells (ASCs) and normal Schwann cells (NSCs) were obtained from adult Wistar ra...
repairing the damaged nerves caused by physical injury (trauma), is one of the major challenges facing modern medical sciences. evening primrose oil (epo) extraction of oenothera biennis seed that enriches with omega-6,γ-linoleic acid and linoleic acid that they have essential role in myelination and neural membrane structure. the aim of this study was to evaluate the functional recovery of sci...
To study the neuropathic pain mechanism, various behavioral responses of animals in to different neuropathic models were considered. Adult male Sprague-Dawley rats weighing 230-280 g were used. Anesthesia was initially induced with pentobarbital I.P. (50 mg/kg). These models included (1): chronic constriction injury (CCI) by loose ligation of the sciatic nerve (2) Spared nerve injury (SNI) by a...
Background: The purpose of this study was to assess the incidence and importance of bony bridge that covers thesupra scapular notch during posterior approach to transfer accessory nerve to suprascapular nerve.Methods: Between 2010 and 2015, the frequency and importance of suprascapular bony bridge instead of transverseligament was assessed among patients with brachial plexus i...
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