OBJECTIVE To report unusual electrophysiologic data in a patient with Tangier disease in an effort to better understand the pathophysiologic features of the peripheral nerve lesions in this disease. DESIGN Case report. PATIENT A 15-year-old girl had subacute onset of asymmetric neuropathy with persistent conduction block, resembling Lewis-Sumner syndrome. MAIN OUTCOME MEASURES Electrophys...

background lumbar plexus block (lpb) is one of the anesthetic options in the elderly patients undergoing hip surgeries. lpb could be safe because it targets somatic nerve in psoas region. effectiveness of lpb is attributed to the sufficient analgesia provided intraoperatively as well as postoperatively. adequate muscle relaxation and immobility during surgery refers to its acceptability. object...

background: carpal tunnel syndrome is the most common neuropathy in the general population. nerve conduction studies are among the standard methods for diagnosing carpal tunnel syndrome. electromyography is painful and unpleasant, and if nerve conduction studies can be used to diagnose axonal injury in carpal tunnel syndrome, electromyography might be replaced. objectives: this study aimed to e...

OBJECTIVES The aim of this study was to investigate whether tramadol had a dose-dependent blocking effect on nerve conduction when administered perineurally to the sural nerve of healthy volunteers. METHODS Twenty-four informed healthy subjects were randomized into four equal groups [Saline (placebo), 0.5% tramadol, 1% tramadol and 1.5% tramadol]. The study was designed to be double-blinded. ...

Edgar Douglas Adrian, a dominating figure of 20th century electrophysiology, published in 1912 a study on the effects of the conduction block induced by application of alcohol vapours to small segments of nerves from which he derived the conclusion that nerve signals regenerate along the nerve fibre during the conduction process. This conclusion was based on results of experiments in which the ...

endoscopic radial artery harvesting (erah) is a feasible and attractive minimally invasive approach for conduit procurement, however there have been concerns about a potential neurological damage occurring at the harvest limb site secondary to injury of the radial nerve during endoscopic harvesting. we present a case of erah in which we evaluated intraoperatively the characteristics of radial n...

Whether the conduction abnormalities and lesions underlying them are randomly distributed throughout the peripheral nervous system (PNS) or certain regions are selectively more vulnerable to attack is an unresolved question in Guillain-Barré syndrome (GBS). To examine this question, 15 cases of GBS were comprehensively examined using electrophysiological techniques which allowed close examinati...

E ntrapment neuropathy of the common peroneal nerve is caused mostly by compression at the fibula head region. In cases of severe axon loss, demonstration of conduction block or reduction of conduction velocity would be difficult. Apart from demyelination, mechanical factors and ischemic mechanisms may play a role. Differing degrees of damage to individual nerve fascicles may occur within the c...

1. Conduction of impulses in peripheral myelinated fibers of a nerve trunk is a continuous process, since with uninjured nerve fibers: (a) within each internodal segment the conduction time increases continuously and linearly with increasing conduction distance; (b) the presence of nodes of Ranvier does not result in any detectable discontinuity in the conduction of the impulse; (c) the ascendi...

In the normal development of connections between motor neurons and muscle fibres, an initial stage of polyneuronal innervation is followed by withdrawal of connections until each muscle fibre is innervated by a single axon. However, polyneuronal innervation has been found to persist after prolonged nerve conduction block, in spite of the resumption of normal neuromuscular activity. Here we anal...