ABSTRACT Background: The prognosis of SLE is int1uenced by the onset of glomerulonephtitis. Clinical ttials in lupus nephritis have demonstrated that cyclophosphamide therapy is the superior regimen in the management oflupus nephritis for preserving renal function. Objective: The purpose of this study is to define the outcome of renal function with bolus pu lses of cyclophosphamide and steroid...

Acute interstitial nephritis is an uncommon renal disorder, causing 2–3% of episodes of acute renal failure Results [1,2]. There are no specific clinical features, and a high index of suspicion together with a readiness to perform The register contained information on 7161 renal renal biopsy in all cases of unexplained renal failure is biopsies in adult patients, 5347 in patients aged <60 requi...

background: in lupus nephritis (ln), deposition of pathogenic autoantibodies in the glomeruli is mediated via cross-reactivity with alpha-actinin. association of serum alpha-actinin antibody (aαa) with ln has been shown in a few studies but the results are controversial. methods: eighty patients into entered the study. the diagnosis of sle was confirmed according to the american college of rheu...

Renal involvement is common in systemic lupus erythematosus (SLE). Anti-C1q antibodies are associated with SLE nephritis. This study attempted to correlate anti-C1q levels to different types of lupus nephritis (LN). Anti-C1q antibodies were assessed in two groups (15 subjects each) of SLE patients with and without LN. Ten apparently healthy volunteers served as controls. The sensitivity of anti...

background: few investigations have focused on the patients with lupus nephritis (ln) and neuropsychiatric systemic lupus erythematosus (npsle). this study was aimed to investigate the clinical features, mortality, and the predictors for mortality of this group of patients. patients and methods: medical records were retrospectively reviewed in sun yat-sen memorial hospital from 1996 to 2012. da...

Forty-three children presenting with acute nephritis were studied for evidence of preceeding steptococcal infection. They were compared with a group of control children of similar age. Two-thirds of those with nephritis gave a history of a preceeding respiratory infection (compared with one-third of the controls). A significant rise of antistreptolysin O tire occurred in only 16 children with n...

A cross-sectional and multicenter study was undertaken to analyze the clinical and immunological characteristics at diagnosis associated with nephritis in northwestern Colombian patients with systemic lupus erythematosus (SLE). Thirty-nine patients with lupus nephritis were included and were compared to 100 SLE patients without nephritis. A multivariate analysis was performed. The patients who ...

The Tubulointerstitial Nephritis and Uveitis syndrome is a very rare condition, probably under-diagnosed in clinical practice. It is characterized by the combination of an interstitial nephritis and uveitis, and is an exclusion diagnosis. Tissue non caseating granuloma can be rarely present, with only 6 cases reported on bone marrow. We present a case of a 55 year old female with a 3-month hist...

objectives this report describes the indication, histopathological patterns, and epidemiology of renal diseases in children in india. patients and methods this is a single-center study on renal biopsies performed between january 2008 and december 2013 in 346 children (age ≤ 14 years). results eleven (3.17%) biopsies were inadequate, and 335 biopsies were considered for analysis. the mean age wa...

Granulomatous interstitial nephritis is an uncommon but potentially reversible cause of impaired kidney function. In the native kidney, granulomatous interstitial nephritis is commonly attributed to drug hypersensitivity, sarcoidosis, or tubulointerstitial nephritis and uveitis, with a significant fraction of cases labelled as ‘idiopathic’ [1]. In kidney transplant recipients, the incidence of ...