CK2 is a serine threonine kinase that participates in a variety of cellular processes with more than 300 defined substrates. This critical enzyme is known to be upregulated in cancers, but the role of this upregulation in carcinogenesis is not yet fully understood but c-myc, one of the defined CK2 substrates, is a well-known proto- oncogene that is normally essential in developmental process bu...

background: regarding the significance of abdominal masses in children, we aimed to identify the pathology of masses according to the age and sex groups. materials and methods: we retrospectively reviewed pathological reports of 461 patients with abdominal mass that underwent resection or biopsy during the study period (25 years). results: one hundred and eighty six cases (40%) were non-neoplas...

conclusions chronic meningitis in immunocompromised hosts can be due to more than one pathologic etiology and we should do all diagnostic evaluation to rule out all possible differential diagnosis. introduction cryptococcal meningitis is a rare disorder that is caused by cryptococcus neoformans in immunocompromised host. case presentation the case was a 64-year-old man with a history of stem ce...

Infection with the human immunodeficiency virus (HIV) leads to a chronic disarmament of the immune system. The process is progressive, having different manifestations as the status of the immune system slowly deteriorates. Some of the most common manifestations of HIV infection are cutaneous in origin, and they can have infectious, neoplastic, or noninfectious or non-neoplastic etiologies. A br...

hepatic inflammatory pseudotumor (ipt) is a rare non-neoplastic process of unknown etiology, generally following a benign inflammatory condition. it is often mistaken as an either primary or metastatic malignancy in imaging studies. we report a 48 year-old female with numerous target lesions (2-4 cm) seen on high resolution ultrasound, spiral ct scan, and mri in all liver lobes compatible with ...