Drs. Levy and Wiersema have provided an authoritative review of the role of endoscopic ultrasonography in the diagnosis and staging of pancreatic cancer. As outlined in their article, endoscopic ultrasound has emerged as an important tool in the diagnostic evaluation of many patients with suspected pancreatic neoplasms. We concur that endoscopic ultrasound is part of the standard preoperative e...

Purpose: Ocular neoplasms, both primary and metastatic, may present with visual disturbance or vision loss often are asymptomatic. Clinical examination demonstrate leukocoria, abnormal pupillary light reflex, a mass lesion without retinal detachment hemorrhage. Retinoblastoma in children uveal melanoma ocular metastases adults the most important malignant neoplasms referred for imaging to aid d...

Abstract Aim The role of PET-CT in oesophageal cancer is controversial. aim this study was to evaluate the utility staging and response evaluation squamous cell carcinoma (SCC) adenocarcinoma (AC). Method Patients undergoing curative-intent treatment were studied prospectively. PET1 carried out at diagnosis repeat scanning (PET2) performed 2-4 weeks post-completion neoadjuvant chemotherapy (nCT...

A novel 3-step random forests methodology involving survival data (survival forests), ordinal data (multiclass forests), and continuous data (regression forests) is introduced for cancer staging. The methodology is illustrated for esophageal cancer using worldwide esophageal cancer collaboration data involving 4627 patients.

BACKGROUND Recent US studies have raised questions as to whether geographic differences in cutaneous melanoma incidence rates are associated with differences in solar ultraviolet (UV) exposure. OBJECTIVES We sought to assess the association of solar UV exposure with melanoma incidence rates among US non-Hispanic whites. METHODS We assessed the association between county-level estimates of a...

Evaluating colorectal lesions by means of radiographic imaging continues to play a major role in detecting and staging cancer of the lower gastrointestinal tract. The diagnosis of large bowel lesions namely Colitis, Vascular and Neoplasm had traditionally been made on the basis of barium enema and/or colonoscopy. Cross sectional imaging as Computed tomography scanning (CT) and MRI plays a pivot...

Primary penile lymphoma is an extremely rare neoplasm. We present a case of 63-year-old man with painless diffuse pe- nile swelling and retention of urine. Biopsy from the penile swelling demonstrated CD20+ diffuse large B-cell lymphoma. Staging was performed using fluorine-18-fluorodeoxyglucose (FDG) positron emission tomography-computed tomography (PET-CT) and revealed a FDG avid penile mass wi...

Malignant cardiac tumors are rare, with an autopsy prevalence of 0.001-0.28% [1]. Benign tumors are more common than malignant, and most initial differential diagnoses for a cardiac mass, when first detected, involve benign lesions. An angiosarcoma is a malignant neoplasm characterized by rapidly proliferating, extensively infiltrating anaplastic cells derived from blood vessels that line irreg...

The role of FDG-PET in oat cell carcinoma of the esophagus is hitherto unexplored. A MEDLINE search using the terms "small cell carcinoma" or "oat cell carcinoma" combined with "FDG-PET" yielded no report on this issue till date. We report, in this article, two cases depicting the usefulness of this modality in the management of this uncommon neoplasm. While reevaluation of unsuspected metastat...

Sections from 90 urinary bladder biopsy specimens were examined by 11 consultant histopathologists with varying experience to determine the appropriateness of existing pathology terminology. Analysis with kappa statistics showed fair to good agreement in the grading and staging of transitional cell carcinoma. There was also reasonable agreement in the diagnosis of high grade dysplasia in random...