BACKGROUND One in eight schoolchildren have an episode of acute infective conjunctivitis every year. Standard clinical practice is to prescribe a topical antibiotic, although the evidence to support this practice is scarce. We undertook a randomised double-blind trial to compare the effectiveness of chloramphenicol eye drops with placebo in children with infective conjunctivitis in primary care...

The aim of this study was to test the diagnostic feasibility of the polymerase chain reaction (PCR) for detection of infections with Chlamydia trachomatis in eye swabs from patients with conjunctivitis, and to establish the basic technique of the PCR for epidemiological survey. The results of the PCR were compared with the Mikro Trak immunofluorescence assay (IFA). From 49 specimens of patients...

Conjunctivitis (Pink eye) is often infectious and caused by either bacterial or viral infections. Ampicillin, gentamicin, nitrofurantoin and cephalexin resistant Enterobacter agglomerans and Pseudomonas aeruginosa were isolated from two cases of acute conjunctivitis in swamp buffaloes in Nagaland,. Treatment with tetracycline eye drop resulted in cure within three days. Isolation of multiple dr...

Background Several agents have been used for the treatment of neonatal hyperbilirubinemia, but the effect of oral fenofibrate on serum bilirubin level was not evaluated so much. The aim of this study was to assess the effect of oral fenofibrate on a total serum bilirubin (TSB) in term neonates with hyperbilirubinemia. Materials and Methods: This clinical trial was done on 80 term neonate with ...

BACKGROUND Despite a long period of development, there are still considerable variations in the spectral output, the levels of irradiance, and irradiated area provided by commercial phototherapy systems. These variations depend on the types and output of the lamps used to produce the phototherapy, along with the design of the systems, and principally on whether the phototherapy is provided from...

Background In recent years, tendency to use drugs has been increasing in the treatment of neonatal jaundice. Several drugs have been used since then, but the effect of probiotics on serum bilirubin level (SBL) is not so clear. This study was conducted to evaluate the effect of probiotics on SBL and the duration of phototherapy in term neonates with hyperbilirubinemia. Materials and Methods: In ...

Hyperbilirubinemia is a common problem during neonatal period especially in preterm neonates. Transcutaneous bilirubin measurement (TcB) by special devices had been documented as an effective tool for predicting neonatal jaundice in full term neonate, but for preterm infants the present evidences are controversial. We carried out a prospective study in Shariati Hospital NICU. 126 paired TcB/tot...

Maldistribution of light is a potential cause of phototherapy failure in the neonate. Differences in light intensity over the surface can be measured with a radiometer as this detects the radiant energy impinging on the incubator mattress. An infant nursed on the front third of the mattress receives less than 40% of the maximal light incident on the centre of the mattress, and consequently degr...

AIMS Differential diagnosis of allergic conjunctivitis or dry eye is sometimes very difficult to diagnose by symptoms and clinical examination alone, especially in older patients. It was hypothesised that clinically allergic patients who were serum antigen specific IgE negative were candidates for dry eye. METHODS Sixty patients were studied prospectively who were clinically diagnosed with al...