BACKGROUND Neonatal infections cause a significant proportion of deaths in the first week of life, yet little is known about risk factors and pathways of transmission for early-onset neonatal sepsis globally. We aimed to estimate the risk of neonatal infection (excluding sexually transmitted diseases [STDs] or congenital infections) in the first seven days of life among newborns of mothers with...

conclusions: in neonates and infants with primary diagnosis of sepsis, hsv infection should be considered especially if the clinical condition does not improve after 48 hours of antibiotic therapy, and sepsis still exists with elevated liver enzymes. results: among 150 neonates and infants younger than 3 months old with sepsis, the pcr results for detecting the hsv dna, were positive in 6 sampl...

BACKGROUND Infection causes neonatal mortality in both high and low income countries. While simple interventions to prevent neonatal infection are available, they are often poorly understood and implemented by clinicians. A basic understanding of healthcare providers' perceptions of infection control provides a platform for improving current practices. Our aim was to explore the views of health...

  Objective(s): Bacterial infection contributes substantially to neonatal morbidity and mortality. Early diagnosis of neonatal sepsis is difficult because clinical signs are non-specific. We have evaluated serum IL-6, 8 and 10 as potential early diagnostic markers of neonatal infection and their relationship to mortality rate and poor prognosis.   Materials and Methods : A total ...

Prof. Alistair G. S. Philip, MD, Division of Neonatal and Development Medicine, Stanford University Medical Center, 750 Welch Road, Suite 135, Palo Alto, CA 94304 (USA) Epidemiology During the past 50 years or so, since the introduction of antibiotics, the predominant organisms causing neonatal sepsis have fluctuated to a considerable extent. In contrast, the characteristics of infants who deve...

Neonates, including mice and humans, are highly susceptible to cytomegalovirus (CMV) infection. However, many aspects of neonatal CMV infections such as viral cell tropism, spatio-temporal distribution of the pathogen as well as genesis of antiviral immunity are unknown. With the use of reporter mutants of the murine cytomegalovirus (MCMV) we identified the lung as a primary target of mucosal i...

Introduction The difficulty to set up a diagnostic model to improve actual medical care results [1], depends on the varieties of clinical presentations for serious infections in the newborn and on his biophysical features. Additionally, many anamnestic risk factors [2] (chorioamnionitis, positive vagino-rectal colture swabs for GBS) or care risk factors (invasive procedures) potentially involve...

THE isolation of stable strains of trachoma virus reported by T'ang, Chang, Huang, and Wang (1957) and confirmed by Collier and Sowa (1958) has made possible the study of the early stages of this infection. Collier, DukeElder, and Jones (1958) have reported studies on blind volunteers and the following account of an accidental laboratory infection is reported as confirmatory evidence that the v...