Intrahepatic cholestasis of pregnancy (ICP) is associated with adverse neonatal survival and is estimated to impact between 0.4 and 5% of pregnancies worldwide. Here we show that maternal cholestasis (due to Abcb11 deficiency) produces neonatal death among all offspring within 24 h of birth due to atelectasis-producing pulmonary hypoxia, which recapitulates the neonatal respiratory distress of ...

Biliary lipid compositions in infants with cholestasis were analysed. Bile acid and phospholipid values were appreciably lower in infants with idiopathic neonatal hepatitis syndrome or corrected biliary atresia than in control infants. Cholesterol values were not, however, notably lower in infants with cholestasis. When biliary lipid components were determined in terms of molar percent, bile ac...

1. Gutiérrez-Larraya Aguado F, Galindo Izquierdo A, Olaizola Llodio I, Velasco Bayón, Merino Batres G, De la Fuente P. Taquicardias supraventriculares fetales. Rev Esp Cardiol. 1996;49:444-50. 2. Wren C. Cardiac arrhythmias in the fetus and newborn. Semin Fetal Neonatal Med. 2006;11:182-90. 3. Jaeggi ET, Nii M. Fetal bradyand tachyarrhythmias: new and accepted diagnostic and treatment methods. ...

Introduction: Neonatal cholestasis due to endocrine diseases is infrequent and poorly reco­ gnized. Referral to the pediatric endocrinologist is delayed. Objective: We characterized cholestasis in infants with congenital pituitary hormone deficiencies (CPHD), and its resolu­ tion after hormone replacement therapy (HRT). Subjects and methods: Sixteen patients (12 males) were included; eleven wit...

1. Gutiérrez-Larraya Aguado F, Galindo Izquierdo A, Olaizola Llodio I, Velasco Bayón, Merino Batres G, De la Fuente P. Taquicardias supraventriculares fetales. Rev Esp Cardiol. 1996;49:444-50. 2. Wren C. Cardiac arrhythmias in the fetus and newborn. Semin Fetal Neonatal Med. 2006;11:182-90. 3. Jaeggi ET, Nii M. Fetal bradyand tachyarrhythmias: new and accepted diagnostic and treatment methods. ...