The FDA has approved a new, once-daily atypical antipsychotic lurasidone (Latuda) for the treatment of schizophrenia in adults.1 According to the manufacturer, the FDA reviewed data from >40 clinical trials involving >2500 patients. The approval was based on results of four 6-week placebo-controlled trials in which lurasidone produced significantly greater improvement than placebo on the Positi...

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background: nowadays, schizophrenia is one of the most important disabling mental disorders in the world. regarding to occupational therapy as one of the most essential treatment for this disorder, the main aim of this study is to determine the effect of it on negative symptoms of schizophrenias patients. methods: this study is a clinical trials research and the samples were 84 schizophrenia pa...

introduction: this study aimed to evaluate the effectiveness of exercise and token‑behavior therapy on the negative symptoms of schizophrenic patients. objective: comparison of the effectiveness of exercise and token‑behavior therapy on the negative symptoms of schizophrenic patients. methods: this research was a randomized controlled clinical trial that was done on 45 schizophrenic patients, h...

conclusions according to this model, students with high score on negative perfectionism by mechanism of academic rumination report higher depressive symptoms, however students with high score on positive perfectionism report lower depressive symptoms through reduction of ruminative thoughts. results preliminary analyses revealed that positive perfectionism was negatively correlated with both de...

Many patients with schizophrenia have negative symptoms, but their evaluation is a challenge. Thus, standardized assessments are needed to facilitate identification of these symptoms. Many tools have been developed, but most are based on observer ratings. Self-evaluation can provide an additional outcome measure and allow patients to be more engaged in their treatment. The aim of this study was...

background: knowledge is limited concerning the role of temperament and character factors on schizophrenia. recent studies suggest that dimensions of temperament and character influence symptoms and functions in schizophrenia.  the purpose of this study was to determine the relationship between temperament and character with positive and negative symptoms in patients with schizophrenia. methods...

Objective: This study aimed to investigate the role of negative and positive affectivity, selffocused attention, and attentional control in social anxiety symptoms.  Methods: A sample of 382 students of Isfahan University was selected and the participants completed Social Phobia Inventory (SPIN), Positive and Negative Affect Schedule (PANAS), Attentional Control Scale (ACS), and Focus...