Early massive edema caused by severe cerebral contusion results in elevation of intracranial pressure (ICP) and clinical deterioration within 24-72 hours post-trauma. Previous studies indicate that cells in the central area of the contusion undergo shrinkage, disintegration, and homogenization, whereas cellular swelling is predominant in the peripheral area, suggesting that early massive edema ...

OBJECTIVE To assess the efficacy of maggot therapy for treating foot and leg ulcers in diabetic patients failing conventional therapy. RESEARCH DESIGN AND METHODS Retrospective comparison of changes in necrotic and total surface area of chronic wounds treated with either maggot therapy or standard (control) surgical or nonsurgical therapy. RESULTS In this cohort of 18 patients with 20 nonhe...

We present the assessment of ex vivo mouse muscle tissue by quantitative parametric imaging of the near-infrared attenuation coefficient µt using optical coherence tomography. The resulting values of the local total attenuation coefficient µt (mean ± standard error) from necrotic lesions in the dystrophic skeletal muscle tissue of mdx mice are higher (9.6 ± 0.3 mm(-1)) than regions from the sam...

T HE POSSIBILITY that the anemia in some cancer patients was due to the hemolytic effect of toxins produced by the tumor was first analyzed by Weil2#{176} in 1908. He demonstrated that extracts of normal human and animal organs had a lytic effect in vitro on red blood cells although there was considerable variability in the hemolytic potency of these extracts. Moreover, he reported that both ne...

this case report describes treatment of a necrotic immature permanent mandibular first molar with pulpal necrosis in 9-year old female with spondyloepiphyseal dysplasia. the coronal half of the root canal was debrided with a file #30 to remove necrotic tissue, and irrigated with chlorhexidine 0.12%. bleeding was evoked to form an intracanal blood clot; the wound was then dressed with calcium hy...

accumulation of soft tissue or dentinal remnants in the apical region is a common event that can cause blockage of root canals. this event can be avoided if apical patency is performed during the root canal shaping procedures. however, there is no consensus on the role of apical patency in relation to the success of endodontic treatment of necrotic teeth with apical periodontitis. therefore, th...

<abstract><p>We propose a multiphase modeling approach to describe glioma pseudopalisade patterning under the influence of acidosis. The phases considered at model onset are glioma, normal tissue, necrotic matter, and interstitial fluid in void-free volume with acidity represented by proton concentration. We start from mass momentum balance characterize respective fractions deduce r...

OBJECTIVE To determine the effects of ibuprofen (Ibp) on the vessel proliferation and necrosis in a rat glioma model. STUDY DESIGN Experimental, randomized interventional trial. PLACE AND DURATION OF STUDY 1st Neurosurgery Clinic in Bakirkoy Mental Diseases Hospital, Bakirkoy, Istanbul, Turkey, in the year 2010. METHODOLOGY After stereotactic injection of C6/LacZ rat glioma cells into the...